Kim Young, Xia Brent T, Chang Alex L, Pritts Timothy A
Department of Surgery and Institute for Military Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0558, the United States.
Int J Hematol Res. 2016 Jun;2(2):124-129. doi: 10.17554/j.issn.2409-3548.2016.02.31. Epub 2016 Jun 27.
Hemorrhagic shock is a leading cause of mortality within the trauma population, and blood transfusion is the standard of care. Leukoreduction filters remove donor leukocytes prior to transfusion of blood products. While the benefits of leukocyte depletion are well documented in scientific literature, these benefits do not translate directly to the clinical setting. This review summarizes current research regarding leukoreduction in the clinical arena, as well as studies performed exclusively in the trauma population.
失血性休克是创伤人群死亡的主要原因,输血是标准治疗方法。白细胞滤除器在输血前可去除供体白细胞。虽然白细胞去除的益处已在科学文献中得到充分证明,但这些益处并未直接转化为临床应用。本综述总结了目前关于临床领域白细胞滤除的研究,以及专门针对创伤人群进行的研究。