Kunik Mark E, Mulsant Benoit H, Rifai A Hind, Sweet Robert, Pasternak Rona, Rosen Jules, Zubenko George S
Geriatric Clinical Research Unit, Dept. of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Am J Geriatr Psychiatry. 1993;1(1):38-45. doi: 10.1097/00019442-199300110-00006. Epub 2013 Jan 28.
We studied 154 patients with major depression, with and without personality disorder (PD), consecutively admitted to a geriatric unit and compared their characteristics and responses to acute inpatient treatment. Thirty-seven patients (24%) met DSM-III-R criteria for PD. PD not otherwise specified and dependent PD were the most frequent PD diagnoses, whereas dramatic cluster PDs were rare. Patients with PD were significantly more likely to have had 1) recurrent depression, 2) an earlier age at first episode, and 3) a concurrent anxiety disorder. There was a higher proportion of patients with PD to have 1) never married, 2) separated or divorced, or 3) attempted suicide. During inpatient stays of similar lengths, both groups received similar treatment and improved to a similar and significant extent.
我们对154例重度抑郁症患者进行了研究，这些患者有无人格障碍（PD），他们连续入住老年病房，并比较了他们的特征以及对急性住院治疗的反应。37例患者（24%）符合DSM-III-R人格障碍标准。未另行规定的人格障碍和依赖型人格障碍是最常见的人格障碍诊断类型，而戏剧性人格障碍组则很罕见。人格障碍患者更有可能出现以下情况：1）复发性抑郁症，2）首次发病年龄较早，3）并发焦虑症。人格障碍患者中，有较高比例的人：1）从未结婚，2）分居或离婚，3）曾试图自杀。在住院时间相似的情况下，两组接受了相似的治疗，并且改善程度相似且显著。
