Asri R I M, Harun W S W, Samykano M, Lah N A C, Ghani S A C, Tarlochan F, Raza M R
Institute of Postgraduate Studies, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Gambang, 26300 Kuantan, Pahang, Malaysia.
Green Research for Advanced Materials Laboratory, Human Engineering Group, Faculty of Mechanical Engineering, Universiti Malaysia Pahang, 26600 Pekan, Pahang, Malaysia.
Mater Sci Eng C Mater Biol Appl. 2017 Aug 1;77:1261-1274. doi: 10.1016/j.msec.2017.04.102. Epub 2017 Apr 20.
Corrosion prevention in biomaterials has become crucial particularly to overcome inflammation and allergic reactions caused by the biomaterials' implants towards the human body. When these metal implants contacted with fluidic environments such as bloodstream and tissue of the body, most of them became mutually highly antagonistic and subsequently promotes corrosion. Biocompatible implants are typically made up of metallic, ceramic, composite and polymers. The present paper specifically focuses on biocompatible metals which favorably used as implants such as 316L stainless steel, cobalt-chromium-molybdenum, pure titanium and titanium-based alloys. This article also takes a close look at the effect of corrosion towards the implant and human body and the mechanism to improve it. Due to this corrosion delinquent, several surface modification techniques have been used to improve the corrosion behavior of biocompatible metals such as deposition of the coating, development of passivation oxide layer and ion beam surface modification. Apart from that, surface texturing methods such as plasma spraying, chemical etching, blasting, electropolishing, and laser treatment which used to improve corrosion behavior are also discussed in detail. Introduction of surface modifications to biocompatible metals is considered as a "best solution" so far to enhanced corrosion resistance performance; besides achieving superior biocompatibility and promoting osseointegration of biocompatible metals and alloys.
生物材料中的腐蚀防护变得至关重要，特别是为了克服生物材料植入人体所引起的炎症和过敏反应。当这些金属植入物与诸如人体血液和组织等流体环境接触时，它们中的大多数会相互产生高度拮抗作用，进而促进腐蚀。生物相容性植入物通常由金属、陶瓷、复合材料和聚合物制成。本文特别关注有利地用作植入物的生物相容性金属，如316L不锈钢、钴铬钼合金、纯钛和钛基合金。本文还深入探讨了腐蚀对植入物和人体的影响以及改善腐蚀的机制。由于这种腐蚀问题，已经采用了几种表面改性技术来改善生物相容性金属的腐蚀行为，如涂层沉积、钝化氧化层的形成和离子束表面改性。除此之外，还详细讨论了用于改善腐蚀行为的表面纹理化方法，如等离子喷涂、化学蚀刻、喷砂、电解抛光和激光处理。对生物相容性金属进行表面改性被认为是迄今为止提高耐腐蚀性能的“最佳解决方案”；此外还能实现卓越的生物相容性，并促进生物相容性金属及合金的骨整合。
