Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, 5988 Renmin Street, Changchun 130025, China; Key Laboratory of Automobile Materials, Ministry of Education, College of Materials Science and Engineering, Jilin University, 5988 Renmin Street, Changchun 130025, China; Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Québec City, Canada.
Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, 5988 Renmin Street, Changchun 130025, China.
J Mech Behav Biomed Mater. 2018 Jan;77:90-105. doi: 10.1016/j.jmbbm.2017.08.035. Epub 2017 Sep 1.
Metallic biomaterials are widely used for clinical applications because of their excellent mechanical properties and good durability. In order to provide essential biofunctionalities, surface functionalization is of particular interest and requirement in the development of high-performance metallic implants. Inspired by the functional surface of natural biological systems, many new designs and conceptions have recently emerged to create multifunctional surfaces with great potential for biomedical applications. This review firstly introduces the metallic biomaterials, important surface properties, and then elaborates some strategies on achieving the bioinspired surface functionalization for metallic biomaterials.
金属生物材料由于其优异的机械性能和良好的耐久性而被广泛应用于临床。为了提供必要的生物功能,表面功能化在高性能金属植入物的开发中具有特别的意义和要求。受天然生物系统功能表面的启发,最近出现了许多新的设计和概念,以创造具有巨大生物医学应用潜力的多功能表面。本文首先介绍了金属生物材料、重要的表面性能,然后阐述了实现金属生物材料仿生表面功能化的一些策略。