Liu Jinghao, Song Zuoqing, Liu Renwang, Liu Minghui, Ren Dian, Zhou Qinghua, Chen Jun
Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.
Zhongguo Fei Ai Za Zhi. 2017 May 20;20(5):361-365. doi: 10.3779/j.issn.1009-3419.2017.05.10.
Metastatic pleomorphic liposarcoma in the mediastinum is rare, and the current treatments are most of the times ineffective. We hereby report a case with relapsed pleomorphic liposarcoma adjacent to the psoas major muscle and with mediastinal metastasis, to discuss the clinical features and treatment strategies of pleomorphic liposarcoma. The patient's clinical history, imaging findings, pathological diagnosis, and multidisciplinary treatments were retrospectively analyzed. A 41-year old female patient was diagnosed with pleomorphic liposarcoma adjacent to the psoas major muscle and mediastinal metastasis. After multidisciplinary treatments, including surgery, chemotherapy, and targeted therapy, the patient has survived 65 months until now. Surgical resection is considered as the first choice of the treatment for pleomorphic liposarcoma. Multidisciplinary treatments, including chemotherapy and other medical treatments, are effective to slow the disease progression and to reduce the disease recurrence.
纵隔转移性多形性脂肪肉瘤较为罕见，目前的治疗方法大多无效。我们在此报告一例复发的多形性脂肪肉瘤，位于腰大肌附近并伴有纵隔转移，以探讨多形性脂肪肉瘤的临床特征及治疗策略。对该患者的临床病史、影像学检查结果、病理诊断及多学科治疗进行了回顾性分析。一名41岁女性患者被诊断为腰大肌附近多形性脂肪肉瘤并伴有纵隔转移。经过包括手术、化疗和靶向治疗在内的多学科治疗后，该患者至今已存活65个月。手术切除被认为是多形性脂肪肉瘤的首选治疗方法。包括化疗和其他药物治疗在内的多学科治疗可有效减缓疾病进展并降低疾病复发率。
