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Application of evolutionary games to modeling carcinogenesis.进化博弈论在致癌发生建模中的应用。
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Investigating prostate cancer tumour-stroma interactions: clinical and biological insights from an evolutionary game.探究前列腺癌肿瘤-基质相互作用:来自进化博弈论的临床与生物学见解。
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具有弱选择的空间进化博弈

Spatial evolutionary games with weak selection.

作者信息

Nanda Mridu, Durrett Richard

机构信息

North Carolina School of Science and Mathematics, Durham, NC 27705.

Math Department, Duke University, Durham NC, 27708-0320

出版信息

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6046-6051. doi: 10.1073/pnas.1620852114. Epub 2017 May 22.

DOI:10.1073/pnas.1620852114
PMID:28533405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5468649/
Abstract

Recently, a rigorous mathematical theory has been developed for spatial games with weak selection, i.e., when the payoff differences between strategies are small. The key to the analysis is that when space and time are suitably rescaled, the spatial model converges to the solution of a partial differential equation (PDE). This approach can be used to analyze all [Formula: see text] games, but there are a number of [Formula: see text] games for which the behavior of the limiting PDE is not known. In this paper, we give rules for determining the behavior of a large class of [Formula: see text] games and check their validity using simulation. In words, the effect of space is equivalent to making changes in the payoff matrix, and once this is done, the behavior of the spatial game can be predicted from the behavior of the replicator equation for the modified game. We say predicted here because in some cases the behavior of the spatial game is different from that of the replicator equation for the modified game. For example, if a rock-paper-scissors game has a replicator equation that spirals out to the boundary, space stabilizes the system and produces an equilibrium.

摘要

最近,针对具有弱选择的空间博弈,即策略之间的收益差异很小时,已经发展出了一种严谨的数学理论。分析的关键在于,当对空间和时间进行适当的重新标度时,空间模型会收敛到一个偏微分方程(PDE)的解。这种方法可用于分析所有[公式:见正文]博弈,但有许多[公式:见正文]博弈,其极限偏微分方程的行为尚不清楚。在本文中,我们给出了确定一大类[公式:见正文]博弈行为的规则,并通过模拟来检验其有效性。简而言之,空间的作用等同于对收益矩阵进行改变,一旦做到这一点,空间博弈的行为就可以从修改后博弈的复制动态方程的行为中预测出来。我们在这里说预测,是因为在某些情况下,空间博弈的行为与修改后博弈的复制动态方程的行为不同。例如,如果一个剪刀石头布博弈的复制动态方程向外螺旋到边界,空间会使系统稳定并产生一个均衡。