Olsen Ane Sophie, Steensberg Alvilda Thougaard, la Cour Morten, Kjaer Troels Wesenberg, Damato Bertil, Pinborg Lars Hageman, Kolko Miriam
Department of Ophthalmology, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Ophthalmic Res. 2017;58(2):85-93. doi: 10.1159/000468942. Epub 2017 May 24.
Unrecognized visual field loss is caused by a range of blinding eye conditions as well as serious brain diseases. The commonest cause of asymptomatic visual field loss is glaucoma. No screening tools have been proven cost-effective. Damato Multifixation Campimetry Online (DMCO), an inexpensive online test, has been evaluated as a future cost-beneficial tool to detect glaucoma. To further validate DMCO, this study aimed to test DMCO in a preselected population with neurological visual field loss.
The study design was an evaluation of a diagnostic test. Patients were included if they had undergone surgery for epilepsy during 2011-2014, resulting in visual field loss. They were examined with DMCO and results were compared with those obtained with the Humphrey Field Analyzer (30:2 SITA-Fast). DMCO sensitivity and specificity were estimated with 95% confidence intervals.
The cohort comprised 40 patients (25 female and 15 male) with a mean age of 39 years (range 17-60 years). The mean visual acuity was >1.0 and all eyes had an intraocular pressure <21 mm Hg. Sensitivity and specificity of DMCO compared to the reference standard were 72.7 and 96.3%, respectively.
DMCO detects moderate-to-severe homonymous quadrantanopia; it can be useful in settings where the current practice is confrontation visual field examination, and where standard conventional perimetry is not available.
未被识别的视野缺损由一系列致盲眼病以及严重脑部疾病引起。无症状视野缺损最常见的原因是青光眼。尚无经证实具有成本效益的筛查工具。达马托多注视视野计在线版（DMCO），一种廉价的在线测试，已被评估为未来检测青光眼的成本效益工具。为进一步验证DMCO，本研究旨在对预先选定的有神经源性视野缺损的人群进行DMCO测试。
研究设计为对一种诊断测试的评估。纳入2011 - 2014年期间因癫痫手术导致视野缺损的患者。他们接受了DMCO检查，并将结果与使用汉弗莱视野分析仪（30:2 SITA - Fast）获得的结果进行比较。用95%置信区间估计DMCO的敏感性和特异性。
该队列包括40例患者（25例女性和15例男性），平均年龄39岁（范围17 - 60岁）。平均视力>1.0，所有眼睛眼压<21 mmHg。与参考标准相比，DMCO的敏感性和特异性分别为72.7%和96.3%。
DMCO可检测中度至重度同向象限盲；在当前采用面对面视野检查且无法进行标准传统视野检查的情况下可能有用。
