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鱼尾葵叶不同提取物的体外抗氧化和抗菌潜力研究

In Vitro Anti-Oxidant and Anti-Microbial Potentiality Investigation of Different Fractions of Caryota urens Leaves.

作者信息

Azam Shofiul, Mahmud Md Kayes, Naquib Md Hamza, Hossain Saad Mosharraf, Alam Mohammad Nazmul, Uddin Md Josim, Sajid Irfan, Hossain Muhammad Sazzad, Karim Md Salimul, Hasan Md Ali

机构信息

Department of Pharmacy, International Islamic University Chittagong, Chittagong-4203, Bangladesh.

Department of Pharmaceutical Sciences, North South University, Dhaka-1229, Bangladesh.

出版信息

Biomedicines. 2016 Jul 27;4(3):17. doi: 10.3390/biomedicines4030017.

Abstract

BACKGROUND

is a member of the Arecaceae family and a common plant in the Southeast Asian region. This plant has been reported as an anti-microbial agent in recent years. Thus, we aimed to find out the MIC (minimum inhibitory concentration) against different pathogenic microorganism.

METHODS

The leaves of were extracted and fractioned using different reagents (chloroform, -hexane and carbon tetrachloride). Disc diffusion method was implemented for the assessment of in vitro anti-microbial potency (500 and 250 µg/disc).

RESULT

The entire fraction showed good effect (with the zone of inhibition 19-25 mm) against both gram positive (, , , ) and gram negative (, , , ) bacterial pathogens and fungal strains (, ). The plants also possess effective free radical scavenging potency with an IC of 130.32 µg/mL.

CONCLUSION

This finding reflects a link between the presence of anti-oxidative material and a substantial anti-microbial activity, and substantiates all previous claims against .

摘要

背景

是棕榈科植物的一员,是东南亚地区的常见植物。近年来,这种植物被报道为一种抗菌剂。因此,我们旨在找出其对不同致病微生物的最低抑菌浓度(MIC)。

方法

的叶子用不同试剂(氯仿、正己烷和四氯化碳)进行提取和分离。采用纸片扩散法评估体外抗菌效力(500和250微克/片)。

结果

整个分离物对革兰氏阳性菌(、、、)、革兰氏阴性菌(、、、)和真菌菌株(、)均显示出良好效果(抑菌圈为19 - 25毫米)。该植物还具有有效的自由基清除能力,半数抑制浓度(IC)为130.32微克/毫升。

结论

这一发现反映了抗氧化物质的存在与显著抗菌活性之间的联系,并证实了之前对的所有说法。

需注意,原文中部分植物名称等关键信息缺失,以上翻译是在现有文本基础上进行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6535/5344256/b83cf90468e7/biomedicines-04-00017-g001.jpg

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