Moraes Renata Mendonça, Alves Fabio Abreu, Carvalho Bruna Fernandes do Carmo, Costa Felipe D'Almeida, Lopes Rodrigo Nascimento, Jaguar Graziella Chagas
Stomatology Department - A.C. Camargo Cancer Center, São Paulo/SP - Brazil.
Stomatology Department - Universidade de São Paulo, São Paulo/SP - Brazil.
Autops Case Rep. 2017 Mar 30;7(1):37-41. doi: 10.4322/acr.2017.003. eCollection 2017 Jan-Mar.
Small cell lung carcinoma (SCLC) is an uncommon tumor characterized by an aggressive behavior with early metastasis, usually to the contralateral lung, liver, brain, and bones. There are only five cases of this particular tumor metastasizing to the oral cavity described in the English literature. We present the case of metastatic SCLC in the mandible with radiographic findings resembling a residual cyst. A 66-year-old man with previous diagnosis and treatment for a SCLC was referred to the Stomatology Department with a history of persistent pain in the mandible 1 year after the inferior right pre-molar tooth extraction. The radiographic exam showed a well-delimited radiolucent area on that extracted tooth's region resembling a residual cyst. Biopsy was performed yielding the diagnosis of metastatic SCLC. The patient was referred to the clinical oncologist for chemotherapy. Although uncommon, this tumor should be included in the differential diagnosis of jawbone lesions, particularly when the patient presents a previous diagnosis of SCLC.
小细胞肺癌（SCLC）是一种罕见的肿瘤，其特点是具有侵袭性，早期即可发生转移，通常转移至对侧肺、肝脏、脑和骨骼。英文文献中仅描述了5例这种特殊肿瘤转移至口腔的病例。我们报告一例下颌骨转移性小细胞肺癌病例，其影像学表现类似残余囊肿。一名66岁男性，既往有小细胞肺癌诊断及治疗史，右下前磨牙拔除1年后因下颌骨持续疼痛被转诊至口腔科。影像学检查显示，拔除牙齿区域有一个边界清晰的透光区，类似残余囊肿。活检确诊为转移性小细胞肺癌。该患者被转诊至临床肿瘤学家处接受化疗。尽管这种肿瘤不常见，但在颌骨病变的鉴别诊断中应考虑到，尤其是当患者既往有小细胞肺癌诊断时。
