Aoun Georges, Hayek Elie, Nasseh Ibrahim
Department of Oral Medicine and Maxillofacial Radiology, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
J Clin Imaging Sci. 2020 May 2;10:27. doi: 10.25259/JCIS_46_2020. eCollection 2020.
Metastatic lesions to the oral cavity are uncommon; they represent between 1 and 3% of all malignant oral neoplasms. In this article, we report a rare case of metastatic urothelial bladder carcinoma in the mandible detected on oral radiographic images and confirmed with multiple imaging modalities. A 67-year-old woman presented to our clinic suffering from pain in the right side of the mandible with a mild swelling. Panoramic radiograph revealed an ill-defined relatively radiolucent lesion in the right mandibular premolar-canine region presenting with permeative changes. Cone-beam computed tomography showed a relatively hypodense lesion with demineralization, interruption of the buccal cortices, and slight thickening and sclerosis of the buccal cortical bone. The patient was referred for further evaluation including additional advanced imaging radiographic techniques (MRI and PET scan) and clinical and histopathological examinations that lead to a final diagnosis of metastatic lesion from an underlying urothelial bladder carcinoma.
口腔转移性病变并不常见；它们占所有口腔恶性肿瘤的1%至3%。在本文中，我们报告了一例罕见的下颌骨转移性膀胱尿路上皮癌病例，该病例通过口腔影像学检查发现，并经多种成像方式确诊。一名67岁女性因下颌骨右侧疼痛伴轻度肿胀前来我院就诊。全景X线片显示右下颌前磨牙-尖牙区有一个边界不清的相对透光区病变，呈现浸润性改变。锥形束计算机断层扫描显示一个相对低密度的病变，伴有骨质脱矿、颊侧皮质中断以及颊侧皮质骨轻度增厚和硬化。患者接受了进一步评估，包括额外的高级影像学检查（MRI和PET扫描）以及临床和组织病理学检查，最终诊断为潜在膀胱尿路上皮癌的转移性病变。
