Dahlbäck Cecilia, Ullmark Jenny Heiman, Rehn Martin, Ringberg Anita, Manjer Jonas
Department of Surgery, Skåne University Hospital, Malmö, Sweden.
Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Breast Cancer Res Treat. 2017 Aug;164(3):679-687. doi: 10.1007/s10549-017-4306-5. Epub 2017 May 23.
A gold standard for evaluation of aesthetic outcome after breast-conserving therapy (BCT) is still lacking. The BCCT.core software has been developed to assess aesthetic result in a standardised way. We aimed to study how the result of BCCT.core after BCT is associated with quality of life, measured with the BREAST-Q™, a validated questionnaire.
Women eligible for BCT were consecutively recruited between February 1st 2008 and January 31st 2012 (n = 653). Photographs of 310 women, taken one year after BCT, were evaluated using the BCCT.core software. The postoperative BCT module of the BREAST-Q™ questionnaire was administered by mail and 348 questionnaires were returned (median 5.5 years after BCT). In all, 216 women had both BCCT.core results and completed BREAST-Q™ questionnaires available.
The results from the BCCT.core evaluation were: excellent n = 49 (15.8%); good n = 178 (57.4%); fair n = 73 (23.5%); poor n = 10 (3.2%). The median BREAST-Q™ score for satisfaction with breasts was 66 [interquartile range (IQR) 57-80] and for psychosocial well-being 82 (IQR 61-100). Poor/fair results on BCCT.core were associated with Q-scores below median for both satisfaction with breasts [odds ratio (OR) 3.4 (confidence interval (CI) 1.7-6.8)] as well as for psychosocial well-being [OR 2.2 (CI 1.1-4.2)].
A statistically significant association between BCCT.core results one year after BCT and quality of life ratings using BREAST-Q™ several years later is shown in this study. This implies that the BCCT.core may be valuable in BCT follow-up and used as a standardised instrument in the evaluation of aesthetic results.
保乳治疗（BCT）后美学效果评估的金标准仍未确立。已开发出BCCT.core软件以标准化方式评估美学结果。我们旨在研究BCT后BCCT.core的结果与采用经过验证的BREAST-Q™问卷测量的生活质量之间的关联。
2008年2月1日至2012年1月31日期间连续招募符合BCT条件的女性（n = 653）。使用BCCT.core软件对BCT一年后拍摄的310名女性的照片进行评估。通过邮件发放BREAST-Q™问卷的术后BCT模块，共收回348份问卷（BCT后中位数为5.5年）。共有216名女性同时具备BCCT.core结果和完整的BREAST-Q™问卷。
BCCT.core评估结果为：优秀n = 49（15.8%）；良好n = 178（57.4%）；中等n = 73（23.5%）；差n = 10（3.2%）。BREAST-Q™中对乳房满意度的中位数评分为66[四分位间距（IQR）57 - 80]，心理社会幸福感评分为82（IQR 61 - 100）。BCCT.core评估结果为差/中等与乳房满意度[比值比（OR）3.4（置信区间（CI）1.7 - 6.8）]以及心理社会幸福感[OR 2.2（CI 1.1 - 4.2）]的Q评分低于中位数相关。
本研究表明，BCT一年后的BCCT.core结果与数年后采用BREAST-Q™进行的生活质量评分之间存在统计学上的显著关联。这意味着BCCT.core在BCT随访中可能具有价值，并可作为评估美学结果的标准化工具。
