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频域光学相干断层扫描(SD-OCT)在点状、斑状及其他视网膜白色病变鉴别诊断中的应用

The use of SD-OCT in the differential diagnosis of dots, spots and other white retinal lesions.

作者信息

Zaharova Elena, Sherman Jerome

机构信息

State University of New York's State College of Optometry, University Eye Center, New York, NY, USA.

SUNY Eye Institute, New York, NY, USA.

出版信息

Eye Brain. 2011 Oct 25;3:69-80. doi: 10.2147/EB.S23208. eCollection 2011.

Abstract

PURPOSE

To demonstrate the utility of a retinal imaging technique using spectral domain optical coherence tomography (SD-OCT) for creating a B-scan layer-by-layer analysis to aid in the differential diagnosis of various retinal dots, spots, and other white lesions.

DESIGN

Review.

METHODS

A retrospective review of imaging studies performed with SD-OCT (Topcon, 3DOCT-2000, Oakland, NJ) at SUNY State College of Optometry.

RESULTS

B-scan layer-by-layer analysis and unique SD-OCT reflectivity patterns of the following retinal white lesions are reviewed in the order of their retinal layer localization: myelinated nerve fiber layer, cotton wool spot, exudates, edema residues, drusen, fundus albipunctatus, Stargardt disease, Bietti crystalline dystrophy, punctate inner choroidopathy (PIC), presumed ocular histoplasmosis syndrome (POHS), post-photocoagulation chorioretinal scarring, and osseous choristoma.

CONCLUSION

The reviewed images demonstrate the utility of SD-OCT in the identification of the unique characteristics of the presented retinal pathologies. SD-OCT is ideal for retinal layer localization of lesions, thus enhancing the differential diagnosis of retinal dots, spots, and other white lesions. Even though true pathognomonic patterns are rare, highly suggestive findings of certain retinal abnormalities often facilitate immediate recognition and diagnosis.

摘要

目的

展示一种利用光谱域光学相干断层扫描(SD-OCT)的视网膜成像技术在创建B扫描逐层分析以辅助各种视网膜点状、斑状及其他白色病变鉴别诊断中的效用。

设计

综述。

方法

对纽约州立大学视光学院使用SD-OCT(拓普康,3DOCT-2000,新泽西州奥克兰)进行的成像研究进行回顾性分析。

结果

按照视网膜层定位顺序,对以下视网膜白色病变的B扫描逐层分析及独特的SD-OCT反射率模式进行综述:有髓神经纤维层、棉绒斑、渗出物、水肿残留、玻璃膜疣、白点状眼底、斯塔加特病、比埃蒂结晶状视网膜色素变性、点状内层脉络膜病变(PIC)、推测性眼组织胞浆菌病综合征(POHS)、光凝后脉络膜视网膜瘢痕形成以及骨化性脉络膜错构瘤。

结论

所回顾的图像证明了SD-OCT在识别所呈现的视网膜病变独特特征方面的效用。SD-OCT对于病变的视网膜层定位非常理想,从而增强了对视网膜点状、斑状及其他白色病变的鉴别诊断。尽管真正的特征性模式很少见,但某些视网膜异常的高度提示性发现通常有助于立即识别和诊断。

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