Sinreih Maša, Štupar Saša, Čemažar Luka, Verdenik Ivan, Frković Grazio Snježana, Smrkolj Špela, Lanišnik Rižner Tea
Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Data Brief. 2017 May 4;12:632-643. doi: 10.1016/j.dib.2017.04.050. eCollection 2017 Jun.
Endometrial cancer is the sixth most common cancer in women worldwide. It is associated with aberrant actions of steroid hormones, estrogens and progesterone, but also with enhanced inflammation and reduced cellular differentiation. Here, we show data on demographic and histopathological characteristics of 51 patients with endometrial cancer, together with data on correlations between the expression of 38 genes involved in estrogen and progesterone actions, inflammation and differentiation, and demographic characteristics. We also show data on changes in gene expression of these 38 genes according to histopathological and clinical characteristics of these patients. This article includes data referenced in the manuscript entitled »STAR and AKR1B10 are down-regulated in high-grade endometrial cancer by Sinreih et al. (in press) [1].
子宫内膜癌是全球女性中第六大常见癌症。它与类固醇激素、雌激素和孕激素的异常作用有关，但也与炎症增强和细胞分化降低有关。在这里，我们展示了51例子宫内膜癌患者的人口统计学和组织病理学特征数据，以及参与雌激素和孕激素作用、炎症和分化的38个基因的表达与人口统计学特征之间的相关性数据。我们还展示了根据这些患者的组织病理学和临床特征，这38个基因的基因表达变化数据。本文包含了Sinreih等人（即将发表）[1]题为《STAR和AKR1B10在高级别子宫内膜癌中下调》的手稿中引用的数据。
