Maleeva A, Milkov V
Akush Ginekol (Mosk). 1991 May(5):55-7.
The action of steroid hormones in the target cell was found to be associated with the presence of specific receptors in the cytoplasm. Uterine, endometrial, and myometrial tissues obtained at hysterectomy for endometrial carcinomatosis and fibromyomas were used. In fibromyomas, the estrogen and progesterone receptors were found to be higher in the cytosol than in the normal myometrium. In endometrial carcinomatosis, the estrogen receptors were in varying quantities: normal, low, or nil in the cytosol, whereas the progesterone receptors were low or nil.
研究发现，类固醇激素在靶细胞中的作用与细胞质中特定受体的存在有关。使用了因子宫内膜癌和纤维瘤行子宫切除术时获取的子宫、子宫内膜和子宫肌层组织。在纤维瘤中，发现胞质溶胶中的雌激素和孕激素受体高于正常子宫肌层。在子宫内膜癌中，雌激素受体数量各异：胞质溶胶中正常、低或无，而孕激素受体低或无。
