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心肌炎:临床概述

Myocarditis: A Clinical Overview.

作者信息

Caforio A L P, Malipiero G, Marcolongo R, Iliceto S

机构信息

Division of Cardiology, Department of Cardiological, Thoracic and Vascular Sciences, Centro "V. Gallucci", University of Padova-Policlinico, Via Giustiniani, 2, 35128, Padova, Italy.

Hematology and Clinical Immunology, Department of Medicine, University of Padua, Padua, Italy.

出版信息

Curr Cardiol Rep. 2017 Jul;19(7):63. doi: 10.1007/s11886-017-0870-x.

DOI:10.1007/s11886-017-0870-x
PMID:28540649
Abstract

PURPOSE OF REVIEW

In this paper we will review the modern diagnostic approach to patients with clinically suspected myocarditis as well as the treatment modalities and strategy in light of up-to-date clinical experience and scientific evidence.

RECENT FINDINGS

Rapidly expanding evidence suggests that myocardial inflammation is frequently underdiagnosed or overlooked in clinical practice, although new therapeutic options have been validated. Moreover, the available evidence suggests that subclinical cardiac involvement has negative prognostic impact on morbidity and mortality and should be actively investigated and adequately treated. Myocarditis represents a growing challenge for physicians, due to increased referral of patients for endomyocardial biopsy (EMB) or cardiac magnetic resonance (CMR), and requires a highly integrated management by a team of caring physicians.

摘要

综述目的

在本文中,我们将根据最新的临床经验和科学证据,回顾对临床疑似心肌炎患者的现代诊断方法以及治疗方式和策略。

最新发现

迅速增加的证据表明,尽管新的治疗选择已得到验证,但在临床实践中,心肌炎症常常被漏诊或忽视。此外,现有证据表明,亚临床心脏受累对发病率和死亡率具有不良预后影响,应积极进行检查并给予充分治疗。由于进行心内膜心肌活检(EMB)或心脏磁共振成像(CMR)检查的患者转诊增加,心肌炎对医生来说是一个日益严峻的挑战,需要由富有爱心的医生团队进行高度综合的管理。

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J Thorac Dis. 2017 Mar;9(3):423-427. doi: 10.21037/jtd.2017.03.103.
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Cardiovascular magnetic resonance imaging pattern at the time of diagnosis of treatment naïve patients with connective tissue diseases.初治结缔组织病患者诊断时的心血管磁共振成像模式
Int J Cardiol. 2017 Jun 1;236:151-156. doi: 10.1016/j.ijcard.2017.01.104. Epub 2017 Feb 1.
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ESC working group position paper on myocardial infarction with non-obstructive coronary arteries.
埃塞俄比亚西北部巴赫达尔市蒂贝贝-吉翁专科医院和阿迪纳斯综合医院疑似小儿心脏病的二维及多普勒经胸超声心动图模式:来自一个低收入和中等收入国家的经验
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Clinical characteristics, diagnosis and management of nivolumab-induced myocarditis.纳武利尤单抗致心肌炎的临床特征、诊断和治疗。
Invest New Drugs. 2024 Feb;42(1):116-126. doi: 10.1007/s10637-024-01421-7. Epub 2024 Jan 23.
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Signal Transduct Target Ther. 2024 Jan 1;9(1):1. doi: 10.1038/s41392-023-01668-1.
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