Thungavelu Yogun, Wang Wei, Lin Peng, Chen Taisheng, Xu Kaixu
a Tianjin First Center Hospital, Tianjin Medical University , Tianjin , China.
b Department of Otorhino-laryngology Head and Neck Surgery , Tianjin First Center Hospital, Otorhinolaryngology Institute of Tianjin , Tianjin , China.
Acta Otolaryngol. 2017 Oct;137(10):1046-1050. doi: 10.1080/00016489.2017.1331375. Epub 2017 May 25.
To investigate the characteristics and clinical utility of vestibular autorotation test (VAT) in patients with vestibular migraine.
This study included two groups, an experimental group (441 patients) and a control group (65 healthy subjects). Both groups undertook VAT; the parameters evaluated were horizontal gain/phase, vertical gain/phase and asymmetry. The differences in VAT results between the two groups were investigated.
There were no statistical differences between the VAT data of the control group when compared to the reference value from the manufacturer (p > .05). There were statistically significant differences in VAT results between the experimental and control group, namely elevated horizontal gain at frequency 2, 3, 4 and 5 Hz, horizontal phase delay at frequency 2, 4, 5 and 6 Hz, elevated vertical gain at frequency 2 6Hz and vertical phase delay at frequency 4 6Hz.
The results of this study using VAT in VM patients demonstrate elevated horizontal gain, vertical gain and delay in horizontal phase, vertical phase. We suggest the application of VAT as a diagnostic tool which may provide objective evidence that can contribute to the diagnosis of VM and also in differential diagnosis.
探讨前庭自旋转试验(VAT)在前庭性偏头痛患者中的特点及临床应用价值。
本研究包括两组,实验组(441例患者)和对照组(65名健康受试者)。两组均进行VAT;评估的参数为水平增益/相位、垂直增益/相位和不对称性。研究两组之间VAT结果的差异。
与制造商提供的参考值相比,对照组的VAT数据无统计学差异(p>0.05)。实验组和对照组的VAT结果存在统计学显著差异,即2、3、4和5Hz频率下水平增益升高,2、4、5和6Hz频率下水平相位延迟,2至6Hz频率下垂直增益升高,4至6Hz频率下垂直相位延迟。
本研究中对前庭性偏头痛患者使用VAT的结果表明,水平增益、垂直增益升高,水平相位和垂直相位延迟。我们建议将VAT作为一种诊断工具应用,其可提供有助于前庭性偏头痛诊断及鉴别诊断的客观证据。