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重复进行头部CT检查?对于接受抗凝或抗血小板治疗且首次头部CT检查结果为阴性的低海拔坠落患者而言并无必要。

Repeat Head CT? Not Necessary for Patients with a Negative Initial Head CT on Anticoagulation or Antiplatelet Therapy Suffering Low-Altitude Falls.

作者信息

Bauman Zachary M, Ruggero John M, Squindo Sunny, McEachin Chris, Jaskot Michelle, Ngo Will, Barnes Scott, Lopez Peter P

出版信息

Am Surg. 2017 May 1;83(5):429-435.

Abstract

Anticoagulation and antiplatelet (ACAP) medications are increasingly prescribed to patients at high risk for falls. Many trauma centers have developed protocols for obtaining repeat head CT (HCT) for patients with low-altitude falls on ACAP therapy. We assess the need for routine scheduled repeat HCT in this population. Prospective, observational analysis of all low-altitude fall (<6 feet) patients on ACAP therapy evaluated at a Level II trauma center. All low-altitude fall patients with visible or suspected head trauma received an initial HCT. Patients were admitted and repeat HCT was obtained 12 hours later or earlier if acute neurologic decline developed. Chi-squared, Fischer exact, t, and Wilcoxon rank-sum tests were used. Statistical significance was defined as P < 0.05. Total of 1501 patients enrolled suffering low-altitude falls with initial HCT. Among them 1379(91.2%) were negative and 122(8.1%) were initially positive for intracranial hemorrhage. Mean age was 79.9 ± 11.4 years, 61 per cent were female and 85 per cent had visible head trauma at presentation. One hundred ninety-nine were excluded secondary to not receiving repeat HCT. Of the 1180 patients with normal initial HCT who underwent repeat HCT, only 7 (0.51%) had delayed intracranial hemorrhage. None of these patients required surgery, major changes in medical management or suffered head trauma-related mortality; 69 per cent were taking aspirin (acetylsalicylic acid, ASA), 19 per cent warfarin, 17 per cent clopidogrel, 6 per cent other anticoagulants, and 11 per cent were on combination therapy. Repeat HCT for patients on any ACAP therapy after low-altitude fall with a negative initial HCT is not necessary. Thorough neurologic examination and close monitoring is as effective as obtaining a repeat HCT.

摘要

抗凝血和抗血小板(ACAP)药物越来越多地被开给跌倒风险高的患者。许多创伤中心已经制定了方案,以便对接受ACAP治疗且有低空坠落史的患者进行重复头颅CT(HCT)检查。我们评估了这一人群中常规安排重复HCT检查的必要性。对在二级创伤中心接受评估的所有接受ACAP治疗的低空坠落(<6英尺)患者进行前瞻性观察分析。所有有明显或疑似头部外伤的低空坠落患者均接受了首次HCT检查。患者入院,如果出现急性神经功能衰退,则在12小时后或更早进行重复HCT检查。使用卡方检验、费舍尔精确检验、t检验和威尔科克森秩和检验。统计学显著性定义为P<0.05。共有1501名患者因低空坠落接受了首次HCT检查。其中1379例(91.2%)颅内出血为阴性,122例(8.1%)最初为阳性。平均年龄为79.9±11.4岁,61%为女性,85%在就诊时有明显的头部外伤。199例因未接受重复HCT检查而被排除。在1180例首次HCT检查正常且接受了重复HCT检查的患者中,只有7例(0.51%)出现了迟发性颅内出血。这些患者均无需手术、重大医疗管理变更或因头部外伤相关死亡;69%的患者服用阿司匹林(乙酰水杨酸,ASA),19%服用华法林,17%服用氯吡格雷,6%服用其他抗凝剂,11%接受联合治疗。对于首次HCT检查为阴性的低空坠落且接受任何ACAP治疗的患者,无需进行重复HCT检查。全面的神经系统检查和密切监测与重复HCT检查同样有效。

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