Duquesne University Mylan School of Pharmacy, Pittsburgh, PA, USA.
University of New England College of Pharmacy, Portland, ME, USA.
Int Dent J. 2017 Oct;67(5):318-325. doi: 10.1111/idj.12303. Epub 2017 May 20.
Patients frequently use medications with potential implications for oral health and dental procedures, yet little is known about the accuracy of medication lists available to dentists. The aims of this study were to describe the frequency and clinical implications of medication discrepancies in the dental record (phase 1) and to evaluate the impact of pharmacist intervention on medication reconciliation processes in dental practice (phase 2).
A prospective, single-centre study evaluating adults receiving dental care was conducted. Discrepancies between the dental record and patient-reported medications were identified through a pharmacist-led medication review and were further evaluated for potential clinical significance based on drug-induced orofacial adverse-effect profiles. A multifaceted pharmacist-led intervention was implemented. Data were analysed using Poisson regression with a significance level set at 0.05.
One-hundred and thirty patients (48% women; mean age 57 years) were interviewed by a clinical pharmacist (100 before intervention and 30 at follow-up). Of 860 medications reported, 618 discrepancies were identified, medication omission being the most common (71.7%). Of medications omitted, 64.6% had potential oral adverse effects, 7.9% could interact with local anaesthetics/vasoconstrictors and 19.1% had potential bleeding effects. The intervention resulted in a reduction in the number of medication discrepancies and medication omissions (P < 0.001).
Medication discrepancies in the dental record occur at an alarming rate and frequently involve medications known to cause oral health problems or complications with dental procedures. A pharmacist-led intervention targeting medication reconciliation processes is an effective strategy for improving the accuracy of the dentist's medication list.
患者经常使用可能影响口腔健康和牙科操作的药物,但对于牙医可用的药物清单的准确性知之甚少。本研究的目的是描述牙科记录中药物差异的频率和临床意义(第 1 阶段),并评估药师干预对牙科实践中药物重整过程的影响(第 2 阶段)。
进行了一项前瞻性、单中心研究,评估接受牙科护理的成年人。通过药剂师主导的药物审查发现了牙科记录和患者报告的药物之间的差异,并根据药物引起的口腔不良反应概况进一步评估了潜在的临床意义。实施了多方面的药剂师主导的干预措施。使用泊松回归分析数据,显著性水平设为 0.05。
130 名患者(48%为女性;平均年龄 57 岁)接受了临床药师的访谈(100 名在干预前,30 名在随访时)。在报告的 860 种药物中,发现了 618 种差异,药物遗漏是最常见的(71.7%)。在遗漏的药物中,64.6%有潜在的口腔不良反应,7.9%可能与局部麻醉剂/血管收缩剂相互作用,19.1%有潜在的出血作用。干预措施导致药物差异和药物遗漏的数量减少(P<0.001)。
牙科记录中的药物差异发生率令人震惊,且经常涉及已知会引起口腔健康问题或与牙科操作并发症的药物。针对药物重整过程的药剂师主导的干预措施是提高牙医药物清单准确性的有效策略。