Beckett Robert D, Crank Christopher W, Wehmeyer Ann
Manchester College School of Pharmacy, Fort Wayne, IN 46805, USA.
J Pharm Pract. 2012 Apr;25(2):136-41. doi: 10.1177/0897190011422605. Epub 2011 Nov 2.
Pharmacists have been shown to improve medication reconciliation at hospital admission. Limited resources may obligate pharmacy departments to target resources for medication reconciliation rather than extend services to the entire hospital. We conducted a prospective, randomized, nonblinded assessment of the effectiveness and feasibility of pharmacist-led admission medication reconciliation for geriatric patients.
Eighty-one geriatric patients were randomized 1:1 to receive medication reconciliation per current hospital practice or to pharmacist-led medication reconciliation at admission. The primary end point was medication profile appropriateness by pharmacist review at 48 hours postadmission. Secondary end points involved in determining the impact and feasibility of this program.
Pharmacist-led medication was superior to standard hospital practice, with 48% of controls and 71% of intervention patients having appropriate medication profiles at 48 hours postadmission (P = .033). Pharmacists identified 116 discrepancies among 81 patients including predominantly omissions (41%) and a composite of wrong dose, route, or frequency (35%). Pharmacists spent a median 15 minutes per patient.
Pharmacists improved admission medication reconciliation for geriatric patients. Pharmacists identified a significant number of discrepancies, including predominantly omissions and wrong dose, dosage form, or frequency. Pharmacists' contributions to medication reconciliation could yield substantial benefit to patient care.
已证明药剂师可改善住院时的用药核对情况。资源有限可能使药房部门必须将资源用于用药核对,而非将服务扩展至整个医院。我们对药剂师主导的老年患者住院用药核对的有效性和可行性进行了一项前瞻性、随机、非盲法评估。
81名老年患者按1:1随机分组,一组按照当前医院常规做法接受用药核对,另一组在住院时接受药剂师主导的用药核对。主要终点是入院后48小时药剂师审核的用药清单适宜性。次要终点涉及确定该项目的影响和可行性。
药剂师主导的用药核对优于标准医院常规做法,在入院后48小时,对照组有48%的患者用药清单适宜,干预组有71%的患者用药清单适宜(P = 0.033)。药剂师在81名患者中发现了116处差异,主要包括遗漏(41%)以及错误剂量、给药途径或频次的综合情况(35%)。药剂师为每位患者平均花费15分钟。
药剂师改善了老年患者的住院用药核对情况。药剂师发现了大量差异,主要包括遗漏以及错误剂量、剂型或频次。药剂师对用药核对的贡献可为患者护理带来显著益处。