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在芬兰的三家医院中,毛细支气管炎的住院管理存在明显的变异性。

Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals.

机构信息

Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland.

Department of Paediatrics, Kuopio University Hospital, Kuopio, Finland.

出版信息

Acta Paediatr. 2017 Sep;106(9):1512-1518. doi: 10.1111/apa.13931. Epub 2017 Jun 16.

Abstract

AIM

Infants hospitalised for bronchiolitis undergo examinations and treatments not supported by current research evidence and we investigated practice variations with regard to Finnish children under the age of two.

METHODS

This prospective, multicentre cohort study was conducted in paediatric units in three university hospitals in Finland from 2008 to 2010. Hospital medical records were reviewed to collect data on clinical course, testing and treatment. Data were analysed separately for children meeting our strict definition of bronchiolitis, aged under 12 months without a history of wheezing, and a loose definition, aged 12-23 months or with a history of wheezing.

RESULTS

The median age of the 408 children was 8.1 months. Clinical management varied between the three hospitals when stratified by strict and loose bronchiolitis subgroup definitions: complete blood counts ranged from 15-95% vs 16-94%, respectively, and the other measures were chest x-ray (16-91% vs 14-72%), intravenous fluids (2-47% vs 2-41%), use of nebulised epinephrine (10-84% vs 7-50%), use of salbutamol (18-21% vs 13-84%) and use of corticosteroids (6-23% vs 60-76%).

CONCLUSION

The clinical management of bronchiolitis varied considerably with regard to the three hospitals and the two definitions of bronchiolitis. A stronger commitment to evidence-based bronchiolitis guidelines is needed in Finland.

摘要

目的

患有细支气管炎的婴儿会接受一些目前没有研究证据支持的检查和治疗,我们研究了芬兰两岁以下儿童在这方面的实践差异。

方法

本前瞻性、多中心队列研究于 2008 年至 2010 年在芬兰三所大学医院的儿科病房进行。对住院病历进行了回顾,以收集临床过程、检查和治疗的数据。根据严格的细支气管炎定义(12 个月以下、无喘息史)和宽松的定义(12-23 个月或有喘息史)分别对满足我们严格定义的细支气管炎、年龄在 12 个月以下且无喘息史的儿童和宽松定义的儿童进行数据分析。

结果

408 名儿童的中位年龄为 8.1 个月。根据严格和宽松的细支气管炎亚组定义,当对三个医院进行分层时,临床管理存在差异:全血细胞计数分别为 15-95%和 16-94%,其他措施分别为胸部 X 线(16-91%和 14-72%)、静脉输液(2-47%和 2-41%)、使用雾化肾上腺素(10-84%和 7-50%)、使用沙丁胺醇(18-21%和 13-84%)和使用皮质类固醇(6-23%和 60-76%)。

结论

细支气管炎的临床管理因医院和细支气管炎的两种定义而存在显著差异。芬兰需要更加坚定地致力于基于证据的细支气管炎指南。

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Viral Bronchiolitis in Children.儿童病毒性细支气管炎
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