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双肾移植技术:一项系统评价。

Dual kidney transplant techniques: A systematic review.

作者信息

Cocco Annelise, Shahrestani Sara, Cocco Nicholas, Hameed Ahmer, Yuen Lawrence, Ryan Brendan, Hawthorne Wayne, Lam Vincent, Pleass Henry

机构信息

Westmead Hospital, Westmead, NSW, Australia.

University of Sydney, Sydney, NSW, Australia.

出版信息

Clin Transplant. 2017 Aug;31(8). doi: 10.1111/ctr.13016. Epub 2017 Jun 23.

Abstract

BACKGROUND

Dual kidney transplantation (DKT) was developed to improve outcomes from transplantation of extended criteria donors (ECD). This study examined which surgical techniques have been reported for DKT and whether any technique had superior patient and graft survival.

METHOD

Electronic databases were searched for published studies mapping to MESH terms: "kidney or renal" AND "transplan*" AND "dual or double." Single case reports, studies of patients less than 18 years old, studies which did not describe the surgical technique, and studies that did not report patient or graft survival were excluded.

RESULTS

Fifteen reports of 434 DKT recipients were identified. Three techniques were described: bilateral placement; unilateral placement with separate anastomoses; and unilateral placement with patch anastomoses. Patient survival across all three techniques was over 95% at 1 year, and graft survival was also similar at over 90%. Rates of delayed graft function were between 20% and 30% across all techniques.

CONCLUSION

The three techniques have equivalent delayed graft function as well as patient and graft survival rates. This is an encouraging result as it means that the surgeon can choose to use the technique which is most appropriate for their own skills and for the patient.

摘要

背景

双肾移植(DKT)旨在改善扩大标准供体(ECD)移植的效果。本研究调查了已报道的DKT手术技术,以及是否有任何技术具有更好的患者和移植物存活率。

方法

在电子数据库中搜索映射到医学主题词(MESH)的已发表研究:“肾脏或肾”以及“移植*”和“双或双份”。排除单例报告、18岁以下患者的研究、未描述手术技术的研究以及未报告患者或移植物存活率的研究。

结果

确定了434例DKT受者的15份报告。描述了三种技术:双侧放置;单侧放置并分别吻合;单侧放置并补片吻合。所有三种技术的患者1年生存率均超过95%,移植物存活率也相似,超过90%。所有技术的移植肾功能延迟发生率在20%至30%之间。

结论

这三种技术的移植肾功能延迟以及患者和移植物存活率相当。这是一个令人鼓舞的结果,因为这意味着外科医生可以选择使用最适合其自身技能和患者的技术。

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