Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Institute of Child Health, University College, London, UK.
Eur Eat Disord Rev. 2017 Sep;25(5):329-343. doi: 10.1002/erv.2523. Epub 2017 May 23.
Intolerance of uncertainty is an empirically supported transdiagnostic construct that may have relevance in understanding eating disorders. We conducted a meta-analysis and systematic review of intolerance of uncertainty in eating disorders using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We calculated random-effects standardised mean differences (SMD) for studies utilising the Intolerance of Uncertainty Scale (IUS) and summarised additional studies descriptively. Women with eating disorders have significantly higher IUS scores compared with healthy controls (SMD = 1.90; 95% C.I. 1.24 to 2.56; p < 0.001). Post hoc meta-analysis revealed significant differences when comparing women with anorexia nervosa with controls (SMD = 2.16; 95% C.I. 1.14 to 3.18; p < 0.001) and women with bulimia nervosa with controls (SMD = 2.03; 95% C.I. 1.30 to 2.75; p < 0.001). Our synthesis of findings suggests that intolerance of uncertainty may represent a vulnerability and maintenance factor for eating disorders and potential target of cognitive, behavioural, interoceptive and affective symptoms. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.
不确定性容忍度是一种经过实证支持的跨诊断结构，它可能与理解饮食失调有关。我们按照系统评价和荟萃分析的首选报告项目（PRISMA）准则，对饮食失调中的不确定性容忍度进行了荟萃分析和系统评价。我们利用不确定性容忍度量表（IUS）计算了研究的随机效应标准化均数差值（SMD），并描述性地总结了其他研究。与健康对照组相比，饮食失调患者的 IUS 评分明显更高（SMD=1.90；95%置信区间 1.24 至 2.56；p<0.001）。事后荟萃分析显示，与对照组相比，神经性厌食症患者（SMD=2.16；95%置信区间 1.14 至 3.18；p<0.001）和神经性贪食症患者（SMD=2.03；95%置信区间 1.30 至 2.75；p<0.001）之间存在显著差异。我们的研究结果综合表明，不确定性容忍度可能是饮食失调的一个脆弱性和维持因素，也是认知、行为、内脏知觉和情感症状的潜在目标。版权所有 © 2017 约翰威立父子公司和饮食失调协会。
