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蓝藻毒素及其他蓝藻次生代谢产物的提取与应用

Extraction and applications of cyanotoxins and other cyanobacterial secondary metabolites.

作者信息

Haque Fatima, Banayan Sara, Yee Josephine, Chiang Yi Wai

机构信息

School of Engineering, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada.

School of Engineering, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada.

出版信息

Chemosphere. 2017 Sep;183:164-175. doi: 10.1016/j.chemosphere.2017.05.106. Epub 2017 May 18.

Abstract

The rapid proliferation of cyanobacteria in bodies of water has caused cyanobacterial blooms, which have become an increasing cause of concern, largely due to the presence of toxic secondary metabolites (or cyanotoxins). Cyanotoxins are the toxins produced by cyanobacteria that may be harmful to surrounding wildlife. They include hepatotoxins, neurotoxins and dermatotoxins, and are classified based on the organs they affect. There are also non-toxic secondary metabolites that include chelators and UV-absorbing compounds. This paper summarizes the optimal techniques for secondary metabolite extraction and the possible useful products that can be obtained from cyanobacteria, with additional focus given to products derived from secondary metabolites. It becomes evident that the potential for their use as biocides, chelators, biofuels, biofertilizers, pharmaceuticals, food and feed, and cosmetics has not yet been comprehensively studied or extensively implemented.

摘要

水体中蓝藻细菌的迅速增殖导致了蓝藻水华,这已成为一个日益令人担忧的问题,主要原因是存在有毒的次生代谢产物(或蓝藻毒素)。蓝藻毒素是蓝藻细菌产生的毒素,可能对周围的野生动物有害。它们包括肝毒素、神经毒素和皮肤毒素,并根据它们所影响的器官进行分类。还有无毒的次生代谢产物,包括螯合剂和紫外线吸收化合物。本文总结了次生代谢产物提取的最佳技术以及可从蓝藻细菌中获得的可能有用的产品,并特别关注次生代谢产物衍生的产品。显而易见,它们作为杀生物剂、螯合剂、生物燃料、生物肥料、药品、食品和饲料以及化妆品的潜在用途尚未得到全面研究或广泛应用。

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