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耦合复发性传染病的同步和混合爆发。

Synchronized and mixed outbreaks of coupled recurrent epidemics.

机构信息

Department of Physics, East China Normal University, Shanghai, 200062, P. R. China.

Levich Institute and Physics Department, City College of New York, New York, New York, 10031, USA.

出版信息

Sci Rep. 2017 May 25;7(1):2424. doi: 10.1038/s41598-017-02661-9.

Abstract

Epidemic spreading has been studied for a long time and most of them are focused on the growing aspect of a single epidemic outbreak. Recently, we extended the study to the case of recurrent epidemics (Sci. Rep. 5, 16010 (2015)) but limited only to a single network. We here report from the real data of coupled regions or cities that the recurrent epidemics in two coupled networks are closely related to each other and can show either synchronized outbreak pattern where outbreaks occur simultaneously in both networks or mixed outbreak pattern where outbreaks occur in one network but do not in another one. To reveal the underlying mechanism, we present a two-layered network model of coupled recurrent epidemics to reproduce the synchronized and mixed outbreak patterns. We show that the synchronized outbreak pattern is preferred to be triggered in two coupled networks with the same average degree while the mixed outbreak pattern is likely to show for the case with different average degrees. Further, we show that the coupling between the two layers tends to suppress the mixed outbreak pattern but enhance the synchronized outbreak pattern. A theoretical analysis based on microscopic Markov-chain approach is presented to explain the numerical results. This finding opens a new window for studying the recurrent epidemics in multi-layered networks.

摘要

传染病的传播已经研究了很长时间,其中大多数研究都集中在单一传染病爆发的增长方面。最近,我们将研究扩展到了复发性传染病的情况(Sci. Rep. 5, 16010 (2015)),但仅限于单个网络。我们从耦合区域或城市的真实数据中报告说,两个耦合网络中的复发性传染病密切相关,它们可能表现为同时在两个网络中爆发的同步爆发模式,或者表现为一个网络中爆发而另一个网络中不爆发的混合爆发模式。为了揭示潜在的机制,我们提出了一个两层耦合复发性传染病网络模型,以再现同步和混合爆发模式。我们表明,在具有相同平均度数的两个耦合网络中,同步爆发模式更有可能被触发,而混合爆发模式更有可能出现在具有不同平均度数的情况下。此外,我们表明,两层之间的耦合倾向于抑制混合爆发模式,但增强同步爆发模式。我们提出了一种基于微观马尔可夫链方法的理论分析来解释数值结果。这一发现为研究多层网络中的复发性传染病开辟了一个新的窗口。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e3b/5445088/093d80d6b4f0/41598_2017_2661_Fig1_HTML.jpg

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