眼镜蛇（眼镜蛇属）毒液酶的比较研究。

A comparative study of cobra (Naja) venom enzymes.

Tan N H, Tan C S

Department of Biochemistry, University of Malaya, Kuala Lumpur, Malaysia.

Comp Biochem Physiol B. 1988;90(4):745-50. doi: 10.1016/0305-0491(88)90329-x.

Abstract

The L-amino acid oxidase, hyaluronidase, alkaline phosphomonoesterase, protease, phosphodiesterase, acetylcholinesterase, phospholipase A and 5'-nucleotidase activities of 47 samples of venoms from all the six species of cobra (Naja), including five subspecies of Naja naja, were examined. 2. The results demonstrated interspecific differences in the venom contents of phospholipase A, acetylcholinesterase, hyaluronidase and phosphodiesterase. These differences in venom enzyme contents can be used for the differentiation of species of the genus Naja. 3. Thus, our results revealed a correlation between the enzyme composition of venom and the taxonomic status of the snake at the species level for the genus Naja.

摘要

检测了眼镜蛇属（Naja）所有六种蛇（包括印度眼镜蛇五个亚种）的47份蛇毒样本的L-氨基酸氧化酶、透明质酸酶、碱性磷酸单酯酶、蛋白酶、磷酸二酯酶、乙酰胆碱酯酶、磷脂酶A和5'-核苷酸酶活性。2. 结果表明，磷脂酶A、乙酰胆碱酯酶、透明质酸酶和磷酸二酯酶的毒液含量存在种间差异。这些毒液酶含量的差异可用于区分眼镜蛇属的物种。3. 因此，我们的结果揭示了眼镜蛇属蛇毒的酶组成与该属蛇在物种水平上的分类地位之间的相关性。