多线平衡稳态自由进动成像在超高场的快速功能成像。
Multiline balanced SSFP for rapid functional imaging at ultrahigh field.
机构信息
Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany.
High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
出版信息
Magn Reson Med. 2018 Feb;79(2):994-1000. doi: 10.1002/mrm.26761. Epub 2017 May 25.
PURPOSE
The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field.
METHODS
Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen-level-dependent (BOLD) signal changes.
RESULTS
With increasing repetition time and echo train length, the BOLD-related signal change as well as the thermal and temporal noise were improved. Activation patterns and signal changes were stable and reproducible across subjects.
CONCLUSIONS
We propose a multiline bSSFP for functional BOLD imaging that approaches the speed of echo-planar imaging and that shows an increased BOLD sensitivity compared with single-line bSSFP. Magn Reson Med 79:994-1000, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
目的
本研究旨在开发和评估一种多线平衡稳态自由进动（bSSFP）序列，用于超高场的带通功能磁共振成像。
方法
在 9.4T 系统上进行了使用视觉任务的带通 bSSFP 功能磁共振成像实验，回波链从一个到七个回波不等。我们分析了采集效率、时间和热信噪比，以及观察到的血氧水平依赖性（BOLD）信号变化。
结果
随着重复时间和回波链长度的增加，BOLD 相关的信号变化以及热和时间噪声得到了改善。在不同的受试者之间，激活模式和信号变化是稳定且可重复的。
结论
我们提出了一种用于功能 BOLD 成像的多线 bSSFP，它接近回波平面成像的速度，并显示出比单线 bSSFP 更高的 BOLD 灵敏度。磁共振医学 79：994-1000，2018。©2017 国际磁共振学会。
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