Milewicz Tomasz, Mrozińska Sandra, Szczepański Wojciech, Białas Magdalena, Kiałka Marta, Doroszewska Katarzyna, Kabzińska-Turek Monika, Wojtyś Andrzej, Ludwin Artur, Chmura Łukasz
Pol J Pathol. 2016;67(4):411-414. doi: 10.5114/pjp.2016.65876.
We present a case of a woman with primary amenorrhea. Ultrasound imaging showed a uterus of normal size but bands of connective tissues at the site of ovaries. A genetic test was done which revealed the XY karyotype. Swyer syndrome was diagnosed. The patient did not report for the follow-up visits. Three years later, the woman reported back because of increasing abdominal circumference. The patient underwent an operation. Radical hysterectomy was performed. Histopathological examination showed dysgerminoma and gonadoblastoma on the left gonad and dysgerminoma on the right one. This case report presents the natural history of Swyer syndrome.
我们报告一例原发性闭经的女性病例。超声成像显示子宫大小正常，但卵巢部位有结缔组织带。进行了基因检测，结果显示为XY核型。诊断为斯维尔综合征。该患者未前来进行随访。三年后，该女性因腹围增加前来复诊。患者接受了手术。进行了根治性子宫切除术。组织病理学检查显示左侧性腺为无性细胞瘤和性腺母细胞瘤，右侧为无性细胞瘤。本病例报告展示了斯维尔综合征的自然病程。
