Koch Anna K, Rabsilber Sybille, Lauche Romy, Kümmel Sherko, Dobos Gustav, Langhorst Jost, Cramer Holger
Centre of Integrative Gastroenterology, Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany.
Department of Gynecology, Certified Breast Center, Malteser Hospital St. Anna, Duisburg, Germany; Breast Unit, Kliniken Essen-Mitte, Essen, Germany.
Maturitas. 2017 Nov;105:95-99. doi: 10.1016/j.maturitas.2017.05.008. Epub 2017 May 13.
Previous research has found that yoga can enhance quality of life and ease menopausal symptoms of breast cancer survivors. The study examined whether self-esteem mediated the effects of yoga on quality of life, fatigue and menopausal symptoms, utilizing validated outcome measures.
This is a secondary analysis of a randomized controlled trial comparing the effects of yoga with those of usual care in 40 breast cancer survivors who suffered from menopausal symptoms. All participants completed all 3 assessments (week 0, week 12, and week 24) and provided full data.
Outcomes were measured using self-rating instruments. Mediation analyses were performed using SPSS.
Self-esteem mediated the effect of yoga on total menopausal symptoms (B=-2.11, 95% BCI [-5.40 to -0.37]), psychological menopausal symptoms (B=-0.94, 95% BCI [-2.30 to -0.01]), and urogenital menopausal symptoms (B=-0.66, 95% BCI [-1.65 to -0.15]), quality of life (B=8.04, 95% BCI [3.15-17.03]), social well-being (B=1.80, 95% BCI [0.54-4.21]), emotional well-being (B=1.62, 95% BCI [0.70-3.34]), functional well-being (B=1.84, 95% BCI [0.59-4.13]), and fatigue (B=4.34, 95% BCI [1.28-9.55]). Self-esteem had no effect on somatovegetative menopausal symptoms (B=-0.50, 95% BCI n.s.) or on physical well-being (B=0.79, 95% BCI n.s.).
Findings support the assumption that self-esteem plays a vital role in the beneficial effect of yoga and that yoga can have long-term benefits for women diagnosed with breast cancer and undergoing menopausal transition.
先前的研究发现，瑜伽可以提高乳腺癌幸存者的生活质量并缓解更年期症状。本研究使用经过验证的结局指标，检验自尊是否介导了瑜伽对生活质量、疲劳和更年期症状的影响。
这是一项随机对照试验的二次分析，比较了瑜伽与常规护理对40名患有更年期症状的乳腺癌幸存者的影响。所有参与者均完成了全部3次评估（第0周、第12周和第24周）并提供了完整数据。
使用自评工具测量结局。使用SPSS进行中介分析。
自尊介导了瑜伽对总更年期症状（B=-2.11，95% BCI [-5.40至-0.37]）、心理更年期症状（B=-0.94，95% BCI [-2.30至-0.01]）和泌尿生殖系统更年期症状（B=-0.66，95% BCI [-1.65至-0.15]）、生活质量（B=8.04，95% BCI [3.15 - 17.03]）、社会幸福感（B=1.80，95% BCI [0.54 - 4.21]）、情绪幸福感（B=1.62，95% BCI [0.70 - 3.34]）、功能幸福感（B=1.84，95% BCI [0.59 - 4.13]）和疲劳（B=4.34，95% BCI [1.28 - 9.55]）的影响。自尊对躯体植物神经更年期症状（B=-0.50，95% BCI无统计学意义）或身体幸福感（B=0.79，95% BCI无统计学意义）没有影响。
研究结果支持以下假设，即自尊在瑜伽的有益作用中起着至关重要的作用，并且瑜伽对被诊断患有乳腺癌且处于更年期过渡阶段的女性可能具有长期益处。
