Maroyi Alfred
Medicinal Plants and Economic Development (MPED) Research Center, Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.
Asian Pac J Trop Med. 2017 Apr;10(4):351-360. doi: 10.1016/j.apjtm.2017.03.021. Epub 2017 Apr 6.
Acacia karroo (A. karroo) has been used as herbal medicine by the indigenous people of southern Africa for several centuries. The potential of A. karroo as herbal medicine, its associated phytochemistry and biological activities are reviewed. The extensive literature survey revealed that A. karroo is traditionally used to treat or manage 32 and five human and animal diseases and ailments, respectively. The species is used as herbal medicine for diseases and ailments such as colds, diarrhoea, dysentery, flu, malaria, sexually transmitted infections (STIs), wounds, and also as colic and ethnoveterinary medicine. Multiple classes of phytochemicals such as flavonoids, phenols, phytosterols, proanthocyanidin, tannin, terpenes as well as several minerals have been identified from leaves and roots of A. karroo. Scientific studies on A. karroo indicate that it has a wide range of pharmacological activities which include antibacterial, antifungal, antigonococcal, antihelmintic, antilisterial, antimalarial, antimycobacterial, antioxidant, HIV-1 reverse transcriptase, anti-inflammatory and analgesic. A. karroo has a lot of potential as a possible source of pharmaceutical products for the treatment of a wide range of both human and animal diseases and ailments. Future research should focus on the mechanisms of action of the different plant parts used as herbal medicines, isolated compounds, their efficacy, toxicity and clinical relevance.
数世纪以来，南非原住民一直将滨刺槐用作草药。本文综述了滨刺槐作为草药的潜力、相关植物化学特性及生物活性。广泛的文献调查显示，滨刺槐传统上分别用于治疗或处理32种人类疾病和5种动物疾病及病痛。该物种被用作治疗感冒、腹泻、痢疾、流感、疟疾、性传播感染、伤口等疾病和病痛的草药，也用于治疗绞痛及作为民族兽医药。已从滨刺槐的叶和根中鉴定出多类植物化学物质，如黄酮类、酚类、植物甾醇、原花青素、单宁、萜类以及多种矿物质。对滨刺槐的科学研究表明，它具有广泛的药理活性，包括抗菌、抗真菌、抗淋球菌、抗蠕虫、抗李斯特菌、抗疟疾、抗分枝杆菌、抗氧化、抑制HIV-1逆转录酶、抗炎和镇痛。滨刺槐作为治疗多种人类和动物疾病及病痛的药品潜在来源具有很大潜力。未来的研究应聚焦于用作草药的不同植物部位、分离化合物的作用机制、它们的功效、毒性及临床相关性。
