Martineau Patrick, Pelletier-Galarneau Matthieu, Bazarjani Sadri
Department of Nuclear Medicine, University of Ottawa, Ottawa, Ontario, Canada.
World J Nucl Med. 2017 Apr-Jun;16(2):172-174. doi: 10.4103/1450-1147.203076.
Calciphylaxis, also known as calcific uremic arteriolopathy, is an uncommon disease, typically found in patients with the end-stage renal disease. Pathophysiological features include small vessel vasculopathy with mural calcification, fibrosis, and thrombosis. The clinical presentation varies but often consists of the necrosis of skin and subcutaneous tissues, with or without visceral organ involvement due to small vessel vasculopathy. This condition has a significant morbidity and mortality, making accurate diagnosis imperative. We present a case of calciphylaxis investigated using planar bone scintigraphy and single-photon emission computed tomography-computed tomography (SPECT-CT). This case stresses the value of SPECT-CT to accurately localize the abnormal uptake in subcutaneous soft tissue microcalcifications and confirms the exact location and extent of pathology.
钙过敏症，也称为钙化性尿毒症性小动脉病，是一种罕见疾病，通常见于终末期肾病患者。其病理生理特征包括伴有壁层钙化、纤维化和血栓形成的小血管血管病变。临床表现各异，但通常包括皮肤和皮下组织坏死，可伴有或不伴有因小血管血管病变导致的内脏器官受累。这种疾病具有较高的发病率和死亡率，因此准确诊断至关重要。我们报告一例使用平面骨闪烁显像和单光子发射计算机断层扫描-计算机断层扫描（SPECT-CT）检查的钙过敏症病例。该病例强调了SPECT-CT在准确定位皮下软组织微钙化异常摄取方面的价值，并证实了病理的确切位置和范围。
