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用于纳米组装胶囊的交联壳：一种用于制备具有极高弛豫率的较小载钆胶囊的新型包封方法。

Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd-loaded capsules with exceedingly high relaxivities.

作者信息

Farashishiko Annah, Plush Sally E, Maier Karley B, Dean Sherry A, Woods Mark

机构信息

Department of Chemistry, Portland State University, 1719 SW 10th Ave, Portland, OR 97201, USA.

出版信息

Chem Commun (Camb). 2017 Jun 8;53(47):6355-6358. doi: 10.1039/c7cc00123a.

DOI:10.1039/c7cc00123a
PMID:28555682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5580261/
Abstract

Nano-assembled capsules can incorporate large payloads of high relaxivity Gd, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd relaxivities (70.7 s mmolal).

摘要

纳米组装胶囊可以容纳大量具有高弛豫率的钆，从而开发出用于磁共振成像（MRI）的高可检测性分子成像剂。人们发现一种基于交联肽的新型封装壳能够提供更小的胶囊（平均直径127纳米），其每钆弛豫率极高（70.7 s/mmol）。

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本文引用的文献

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