Cho Hyun-Kyung, Kee Changwon, Yang Heon, Huh Hyoun Do, Kim Su Jin, Park Young Min, Park Jong Moon
Department of Ophthalmology, Gyeongsang National University Changwon Hospital, Gyeongsang National University, School of Medicine, Changwon, Korea.
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Acta Ophthalmol. 2017 Nov;95(7):e539-e547. doi: 10.1111/aos.13450. Epub 2017 May 27.
To compare the quantitative changes of peripheral angle after laser iridotomy (LI) alone (group A) or combined LI and Iridoplasty (group B) using iridotrabecular contact (ITC) index by swept-source anterior segment optical coherence tomography (AS-OCT).
In this prospective comparative observational study, OCT images were obtained before and after the procedure. In each image frame, scleral spur (SS) and the ITC end point (EP) were marked and ITC index was calculated as a percentage of the angle closure from 360°. Age, gender, diagnosis and initial ITC index in Group B were matched with group A. Changes in ITC index, anterior chamber angle parameters, and intraocular pressure (IOP) were inspected.
Thirty-three eyes (20 patients) with shallow anterior chamber were included in each group. Initial ITC index and initial IOP were not significantly different between the two groups (both p > 0.05). However, ITC index and IOP after the procedure were significantly lower in group B than those in group A (ITC index: 31.3 ± 23.2 in group A, 19.0 ± 21.3 in group B, p = 0.011, IOP: p = 0.004). All anterior chamber angle parameters in group B and all parameters in group A except nasal trabecular-iris angles (TIA) were significantly increased after the laser procedure (all p < 0.05).
In patients with shallow anterior chamber, combined LI and Iridoplasty may open the peripheral angle better than LI alone. Iridoplasty may be able to additionally relieve the peripheral angle closure caused by other mechanisms than pupillary block.
使用扫频源眼前节光学相干断层扫描(AS - OCT)的虹膜小梁接触(ITC)指数,比较单纯激光虹膜切开术(A组)或联合激光虹膜切开术与虹膜成形术(B组)后周边房角的定量变化。
在这项前瞻性比较观察研究中,在手术前后获取OCT图像。在每个图像帧中,标记巩膜突(SS)和ITC终点(EP),并计算ITC指数,以360°房角关闭的百分比表示。B组的年龄、性别、诊断和初始ITC指数与A组匹配。检查ITC指数、前房角参数和眼压(IOP)的变化。
每组纳入33只浅前房眼(20例患者)。两组之间的初始ITC指数和初始IOP无显著差异(均p>0.05)。然而,术后B组的ITC指数和IOP显著低于A组(ITC指数:A组为31.3±23.2,B组为19.0±21.3,p = 0.011;IOP:p = 0.004)。激光手术后,B组的所有前房角参数以及A组除鼻侧小梁 - 虹膜角(TIA)外的所有参数均显著增加(均p<0.05)。
对于浅前房患者,联合激光虹膜切开术与虹膜成形术可能比单纯激光虹膜切开术能更好地开放周边房角。虹膜成形术可能能够额外缓解由瞳孔阻滞以外的其他机制引起的周边房角关闭。