Cho Hyun-Kyung, Choae Wooseok
Department of Ophthalmology, School of Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University, Changwon 51472, Korea.
lnstitute of Health Sciences, School of Medicine, Gyeongsang National University, Jinju 52727, Korea.
J Clin Med. 2022 Feb 3;11(3):813. doi: 10.3390/jcm11030813.
To investigate the outcomes of corneal and anterior chamber angle (ACA) parameters after laser iridotomy (LI) combined with peripheral iridoplasty (PI) using dual Scheimpflug analyzer in the long term.
Fifty-eight eyes (58 subjects) with shallow AC were included in this prospective cohort study. Images of the Dual Scheimpflug analyzer were obtained before, 1 week, and 1 year after LI and PI. Pachymetry from three zones (central, middle, and peripheral), corneal aberration, and spherical equivalent (SE) were acquired. AC depth (ACD), AC volume (ACV), ACA from four quadrants, and intraocular pressure (IOP) were also obtained. For comparison of the results, the linear mixed-effects model was employed.
ACD significantly increased from 2.09 ± 0.25 mm to 2.10 ± 0.23 mm at 1 year after laser (all 0.05). ACV and ACA increased significantly after laser at 1 year (all 0.05). IOP significantly decreased from 15.97 ± 4.20 mmHg to 13.73 ± 2.63 mmHg at 1 year (all 0.0001). No significant changes were found in the coma, trefoil, total corneal aberration, pachymetry from three zones, corneal volume, central corneal thickness, and SE after LI and PI until 1 year (all > 0.05).
LI plus PI ameliorated parameters of ACA efficiently and significantly reduced IOP in eyes with shallow AC until 1 year of long-term follow-up. However, parameters of the cornea and SE were not influenced by LI with PI until after 1 year.
长期使用双Scheimpflug分析仪研究激光虹膜切开术(LI)联合周边虹膜成形术(PI)后角膜和前房角(ACA)参数的结果。
本前瞻性队列研究纳入了58只浅前房眼睛(58名受试者)。在LI和PI术前、术后1周及1年获取双Scheimpflug分析仪图像。采集三个区域(中央、中间和周边)的角膜厚度、角膜像差和等效球镜度(SE)。还获取前房深度(ACD)、前房容积(ACV)、四个象限的ACA以及眼压(IOP)。为比较结果,采用线性混合效应模型。
激光术后1年,ACD从2.09±0.25mm显著增加至2.10±0.23mm(均P<0.05)。激光术后1年,ACV和ACA显著增加(均P<0.05)。1年时,IOP从15.97±4.20mmHg显著降至13.73±2.63mmHg(均P<0.0001)。LI和PI术后直至1年,彗差、三叶草像差、总角膜像差、三个区域的角膜厚度、角膜容积、中央角膜厚度和SE均无显著变化(均P>0.05)。
在长达1年的长期随访中,LI联合PI有效改善了ACA参数,并显著降低了浅前房眼睛的IOP。然而,角膜参数和SE在LI联合PI术后1年才受到影响。