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墨西哥新莱昂州蒙特雷市单姓和复姓人群ABO、Rh(D)及MN血型的基因频率与混合估计

Gene frequencies and admixture estimates for ABO, Rh (D), and MN blood groups in persons with mono- and polyphletic surnames in monterrey, N.L., Mexico.

作者信息

Garza-Chapa Raul, Davila-Rodriguez Martha I, Leal-Garza Carlos H, Gonzalez-Quiroga Guillermo, de Los Angeles Rojas-Alvarado Ma

机构信息

Subjefatura de Investigación Científica, Centro de Investigación Biomédica del Noreste, I.M.S.S., Apartado Postal 20, 64720 Monterrey, N.L., México.

出版信息

Am J Hum Biol. 1995;7(1):65-75. doi: 10.1002/ajhb.1310070109.

DOI:10.1002/ajhb.1310070109
PMID:28557230
Abstract

A sample of 3,211 males and females insured by the Instituto Mexicano del Seguro Social (I.M.S.S.) residing in the Monterrey Metropolitan Area (MMA), northeastern Mexico, were selected by their monophyletic or polyphyletic surnames. ABO, Rh (D), and MN blood groups were determined, and phenotype and gene frequencies were estimated to study the genetic variation among populations with these surnames, to estimate the genetic contribution from their most important ancestral populations, both Spanish and Mexican Indians, and to compare genetic structure with other populations that have been reported from this MMA and other urban centers in Mexico with the hypothesis that the persons with monophyletic surnames are the closest descendants of the founders, who colonized the MMA between 1577 and 1596, and that they still conserve some degree of genetic isolation. The results indicate that the selected persons with monophyletic surnames are the closest to the Spanish, supporting the above hypothesis; on the other hand, persons with polyphyletic surnames are the closet to other Mestizo populations from central Mexico and the Mexican Indians. Hybrid persons with one monophyletic and one polyphyletic surname are closer to the monophyletics due to the fact that 90% of these polyphyletics originated in northeastern Mexico. It is concluded that, at present, the Mestizo population from the MMA is integrated by two subpopulations, one with monophyletic and the other with polyphyletic surnames. It is suggested that due to an increase in migration in Mexico, the Mestizo genetic structure of the MMA population will slowly become more uniform. © 1995 Wiley-Liss, Inc.

摘要

从居住在墨西哥东北部蒙特雷大都市区(MMA)、由墨西哥社会保障局(I.M.S.S.)承保的3211名男性和女性中,按照他们的单系或多系姓氏进行抽样。测定ABO、Rh(D)和MN血型,并估计表型和基因频率,以研究这些姓氏人群之间的遗传变异,估计其最重要的祖先群体(西班牙人和墨西哥印第安人)的遗传贡献,并将遗传结构与该MMA以及墨西哥其他城市中心报道的其他人群进行比较,假设单系姓氏的人是1577年至1596年间殖民MMA的奠基者的最亲近后代,并且他们仍然保持一定程度的遗传隔离。结果表明,所选的单系姓氏的人最接近西班牙人,支持了上述假设;另一方面,多系姓氏的人最接近来自墨西哥中部的其他混血人群和墨西哥印第安人。拥有一个单系和一个多系姓氏的混血儿更接近单系姓氏的人,因为这些多系姓氏的人中有90%起源于墨西哥东北部。得出的结论是,目前,MMA的混血人群由两个亚群组成,一个是单系姓氏人群,另一个是多系姓氏人群。有人提出,由于墨西哥移民增加,MMA人群的混血遗传结构将慢慢变得更加均匀。© 1995威利 - 利斯公司。

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