Ndukwe Ikenna E, Shchukina Alexandra, Zorin Vadim, Cobas Carlos, Kazimierczuk Krzysztof, Butts Craig P
Department of Chemistry, University of Bristol, Cantocks Close, Bristol., BS8 1TS, UK.
Department of Pure and Industrial Chemistry, Abia State University, Uturu, PMB 2000., Abia State, Nigeria.
Chemphyschem. 2017 Aug 5;18(15):2081-2087. doi: 10.1002/cphc.201700474. Epub 2017 Jun 8.
Pseudo-2D NMR spectroscopy provides a means of acquiring broadband homonuclear decoupled spectra useful for structural characterization of complex molecules. However, data points concatenated in the direct dimension in these experiments are acquired over incremented time periods-leading to long acquisition times with no sensitivity benefits due to the absence of signal averaging between scans. Herein, the concept of EXACT NMR spectroscopy ("burst" non-uniform sampling of data points) is explored in pseudo-2D experiments with results revealing little or no loss in spectral quality or signal intensity despite the acceleration of acquisition-up to 400 % in some cases.
伪二维核磁共振光谱提供了一种获取宽带同核去耦光谱的方法，这对于复杂分子的结构表征很有用。然而，在这些实验中，直接维度上连接的数据点是在递增的时间段内采集的，这导致采集时间很长，而且由于扫描之间没有信号平均，因此没有灵敏度优势。在此，在伪二维实验中探索了精确核磁共振光谱的概念（数据点的“突发”非均匀采样），结果表明，尽管采集加速，在某些情况下高达400%，但光谱质量或信号强度几乎没有损失。
