Farber Harold J, Silveira Edwin A, Vicere Douglas R, Kothari Viral D, Giardino Angelo P
Section of Pulmonology and
Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas; and.
Pediatrics. 2017 May;139(5). doi: 10.1542/peds.2016-4146. Epub 2017 Apr 10.
Short courses of oral corticosteroid (OCS) medication are recommended for treatment of moderate to severe asthma exacerbations. Concern has been raised about OCS overuse. Our objective is to describe rates of OCS dispensing among children with asthma and factors associated with variation in OCS dispensing.
Claims data for children 1 to <18 years of age with an asthma diagnosis between January 2011 and January 2016 were extracted from the computerized databases of Texas Children's Health Plan.
In the years 2011 to 2015, 17.1% to 21.8% of children had an asthma diagnosis. In each of these years 42.1% to 44.2% of these children had ≥1 OCS dispensing. OCS dispensing rates were higher for the children 1 to 4 years of age compared with older children. Repeated OCS dispensing was common, and was most common for children 1 to 4 years of age. Most children with an OCS dispensing (81%-83%) did not have other utilization suggesting poor asthma control (excessive β-agonist refills, emergency department visit, or hospitalization for asthma). OCSs were less commonly prescribed to patients whose primary care provider was a board-certified pediatrician compared with other types of primary care providers. There was large variation in OCS prescribing rates among pediatricians (15%-86%). There were minimal differences in asthma emergency department visits and no differences in hospitalization rates by the pediatrician's OCS dispensing rate quartile.
The patterns of dispensing observed suggest substantial overprescribing of OCS for children with an asthma diagnosis.
推荐使用短期口服皮质类固醇(OCS)药物治疗中度至重度哮喘急性发作。人们对OCS的过度使用表示担忧。我们的目的是描述哮喘患儿中OCS的配药率以及与OCS配药差异相关的因素。
从德克萨斯儿童健康计划的计算机数据库中提取2011年1月至2016年1月期间1至18岁哮喘诊断患儿的理赔数据。
在2011年至2015年期间,17.1%至21.8%的儿童被诊断为哮喘。在这些年份中,每年有42.1%至44.2%的这些儿童有≥1次OCS配药。1至4岁儿童的OCS配药率高于年龄较大的儿童。重复OCS配药很常见,在1至4岁儿童中最为常见。大多数有OCS配药的儿童(81%-83%)没有其他表明哮喘控制不佳的用药情况(过量的β-激动剂补充剂、急诊就诊或因哮喘住院)。与其他类型的初级保健提供者相比,初级保健提供者为获得委员会认证的儿科医生的患者较少开具OCS。儿科医生之间的OCS处方率差异很大(15%-86%)。根据儿科医生的OCS配药率四分位数,哮喘急诊就诊率差异最小,住院率无差异。
观察到的配药模式表明,哮喘诊断患儿的OCS存在大量过度处方情况。