Crisan-Dabija Radu, Sandu Ioan Gabriel, Popa Iolanda Valentina, Scripcariu Dragos-Viorel, Covic Adrian, Burlacu Alexandru
Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Pulmonology Department, Clinic of Pulmonary Diseases, 700115 Iasi, Romania.
Healthcare (Basel). 2021 Nov 22;9(11):1604. doi: 10.3390/healthcare9111604.
The increasing production of modern medication emerges as a new source of environmental pollution. The scientific community is interested in developing alternative, ecological therapies in asthma. Halotherapy proved its benefits in asthma diagnosis, treatment, and prevention and may represent a reliable therapeutic addition to the allopathic treatment, due to its ecological and environment-friendly nature, in order to prevent or prolong the time to exacerbations in patients with asthma. We aimed to review up-to-date research regarding halotherapy benefits in asthma comprehensively. We searched the electronic databases of PubMed, MEDLINE, EMBASE for studies that evaluated the exposure of asthmatic patients to halotherapy. Eighteen original articles on asthma were included. Five studies in adults and five in children assessed the performance of hypertonic saline bronchial challenges to diagnose asthma or vocal cord dysfunction in asthmatic patients. Three papers evaluated the beneficial effects of halotherapy on mucociliary clearance in asthmatic adults. The therapeutic effect of halotherapy on acute or chronic asthma was appraised in three studies in adults and one in children. The preventive role was documented in one paper reporting the ability of halotherapy to hinder nocturnal asthma exacerbations. All studies seem to sustain the overall positive effects of halotherapy as adjuvant therapy on asthma patients with no reported adverse events. Halotherapy is a crucial natural ally in asthma, but further evidence-based studies on larger populations are needed.
现代药物产量的不断增加成为一种新的环境污染源。科学界对开发哮喘的替代生态疗法很感兴趣。盐疗法已在哮喘的诊断、治疗和预防中证明了其益处，并且由于其生态环保的特性，它可能是对抗疗法治疗的一种可靠补充疗法，有助于预防或延长哮喘患者病情加重的时间。我们旨在全面回顾关于盐疗法对哮喘益处的最新研究。我们在PubMed、MEDLINE、EMBASE等电子数据库中搜索了评估哮喘患者接受盐疗法情况的研究。共纳入了18篇关于哮喘的原创文章。其中5项针对成人的研究和5项针对儿童的研究评估了高渗盐水支气管激发试验在诊断哮喘或哮喘患者声带功能障碍方面的表现。3篇论文评估了盐疗法对成年哮喘患者黏液纤毛清除功能的有益作用。3项针对成人的研究和1项针对儿童的研究评估了盐疗法对急性或慢性哮喘的治疗效果。1篇论文记录了盐疗法预防夜间哮喘发作的作用。所有研究似乎都支持盐疗法作为辅助疗法对哮喘患者具有总体积极效果，且未报告不良事件。盐疗法是哮喘治疗中重要的天然辅助手段，但还需要对更多人群进行进一步的循证研究。
