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不同时长有氧运动对未受过训练女性心血管健康的影响:一项荟萃分析和元回归分析

Effects of different durations of aerobic exercise on the cardiovascular health in untrained women: a meta-analysis and meta-regression.

作者信息

Zhang Yahui, Xu Lisheng, Zhang Xiaodong, Yao Yang, Sun Yingxian, Qi Lin

机构信息

Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang, China.

Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang, China -

出版信息

J Sports Med Phys Fitness. 2018 Oct;58(10):1525-1536. doi: 10.23736/S0022-4707.17.07029-3. Epub 2017 May 30.

DOI:10.23736/S0022-4707.17.07029-3
PMID:28558443
Abstract

INTRODUCTION

Women's cardiovascular health is a hot topic. Exercise intervention is an effective method to improve the cardiovascular functions. The aim of this study was to systematically assess effects of aerobic exercise at different durations on the cardiovascular health of untrained women.

EVIDENCE ACQUISITION

Published articles from January 1989 to March 2016 were identified using electronic databases (PubMed, Cochrane Library, Embase and Web of Science) for randomized controlled trials. Weighted mean differences and 95% confidence intervals (CI) were calculated using fixed-effects and random-effects models. Meta-regression and subgroup analysis were performed to explore the possible heterogeneity.

EVIDENCE SYNTHESIS

Data from 26 published studies with a total of 518 untrained women were identified. The subgroup analysis and meta-regression were performed according to age (under 40, and from 41 to 60 years old) and exercise durations. Maximal oxygen consumption significantly increased at short-duration exercise (95% CI: -2.51 to -1.57; I2=0%) and mid-duration exercise (95% CI: -8.23 to -5.18; I2=0%). While HR (95% CI: 4.72 to 5.60; I2=0%) and SBP (95% CI: 5.55 to 7.52; I2=0%) significantly decreased at mid-duration exercise. Total cholesterol (N.=242, 95% CI: 0.07 to 0.16, I2=13%), HDL-C (N.=242, 95% CI: -0.11 to -0.06, I2=11%) and low-density lipoprotein cholesterol levels (N.=238, 95% CI: 0.07 to 0.16, I2=37%) significantly improved with short-duration, mid-duration and long-duration.

CONCLUSIONS

Improvement of cardiovascular functions decreases with age in untrained women. Short-duration exercise has significant effects on aerobic capacity. Mid-duration exercise significantly improves on aerobic capacity, heart rate and systolic blood pressure. All the different durations of aerobic exercise improve the cholesterol metabolism.

摘要

引言

女性心血管健康是一个热门话题。运动干预是改善心血管功能的有效方法。本研究旨在系统评估不同时长有氧运动对未受过训练女性心血管健康的影响。

证据获取

使用电子数据库(PubMed、Cochrane图书馆、Embase和科学网)检索1989年1月至2016年3月发表的关于随机对照试验的文章。使用固定效应和随机效应模型计算加权平均差和95%置信区间(CI)。进行Meta回归和亚组分析以探讨可能的异质性。

证据综合

共纳入26项已发表研究中的518名未受过训练的女性的数据。根据年龄(40岁以下和41至60岁)和运动时长进行亚组分析和Meta回归。短时长运动(95%CI:-2.51至-1.57;I2=0%)和中时长运动(95%CI:-8.23至-5.18;I2=0%)时最大摄氧量显著增加。中时长运动时心率(95%CI:4.72至5.60;I2=0%)和收缩压(95%CI:5.55至7.52;I2=0%)显著降低。短时长、中时长和长时长运动时总胆固醇(N=242,95%CI:0.07至0.16,I2=13%)、高密度脂蛋白胆固醇(HDL-C,N=242,95%CI:-0.11至-0.06,I2=11%)和低密度脂蛋白胆固醇水平(N=238,95%CI:0.07至0.16,I2=37%)均显著改善。

结论

未受过训练的女性心血管功能的改善随年龄增长而降低。短时长运动对有氧能力有显著影响。中时长运动能显著改善有氧能力、心率和收缩压。所有不同时长的有氧运动均可改善胆固醇代谢。

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