身体疼痛很常见,且与注射吸毒者使用非医疗处方阿片类药物有关。

Physical pain is common and associated with nonmedical prescription opioid use among people who inject drugs.

作者信息

Dahlman Disa, Kral Alex H, Wenger Lynn, Hakansson Anders, Novak Scott P

机构信息

Department of Clinical Sciences Lund, Division of Psychiatry, Lund University, Lund, Sweden.

Malmo Addiction Centre, Clinical Research Unit, Sodra Forstadsg. 35, plan 4, SE-205 02, Malmo, Sweden.

出版信息

Subst Abuse Treat Prev Policy. 2017 May 30;12(1):29. doi: 10.1186/s13011-017-0112-7.

Abstract

BACKGROUND

People who inject drugs (PWID) often have poor health and lack access to health care. The aim of this study was to examine whether PWID engage in self-treatment through nonmedical prescription opioid use (NMPOU). We describe the prevalence and features of self-reported physical pain and its association with NMPOU.

METHODS

PWID (N = 702) in San Francisco, California (age 18+) were recruited to complete interviewer administered surveys between 2011 and 2013. Multivariate logistic regression analysis was conducted to examine the associations among self-reported pain dimensions (past 24-h average pain, pain interference with functional domains) and NMPOU, controlling for age, sex, psychiatric illness, opioid substitution treatment, homelessness, street heroin use and unmet healthcare needs.

RESULTS

Almost half of the sample reported pain, based on self-reported measures in the 24 h before their interview. The most common pain locations were to their back and lower extremities. Past 24-h NMPOU was common (14.7%) and associated with past 24 h average pain intensity on a 10 point self-rating scale (adjusted odds ratio [AOR] = 2.15, 95% confidence interval [CI] 1.21-3.80), and past 24 h pain interference with general activity (AOR 1.82 [95% CI 1.04-3.21]), walking ability (AOR 2.52 [95% CI 1.37-4.63]), physical ability (AOR 2.01 [95% CI 1.16-3.45]), sleep (AOR 1.98 [95% CI 1.13-3.48]) and enjoyment of life (AOR 1.79 [95% CI 1.02-3.15]).

CONCLUSION

Both pain and NMPOU are common among PWID, and highly correlated in this study. These findings suggest that greater efforts are needed to direct preventive health and services toward this population.

摘要

背景

注射毒品者(PWID)往往健康状况不佳且难以获得医疗保健服务。本研究的目的是调查注射毒品者是否通过非医疗处方使用阿片类药物(NMPOU)进行自我治疗。我们描述了自我报告的身体疼痛的患病率和特征及其与非医疗处方使用阿片类药物的关联。

方法

2011年至2013年期间,招募了加利福尼亚州旧金山年龄在18岁及以上的注射毒品者(N = 702),以完成由访员进行的调查。进行多变量逻辑回归分析,以研究自我报告的疼痛维度(过去24小时平均疼痛、疼痛对功能领域的干扰)与非医疗处方使用阿片类药物之间的关联,并控制年龄、性别、精神疾病、阿片类药物替代治疗、无家可归、街头海洛因使用和未满足的医疗需求。

结果

根据访谈前24小时的自我报告测量,近一半的样本报告有疼痛。最常见的疼痛部位是背部和下肢。过去24小时的非医疗处方使用阿片类药物情况很常见(14.7%),并且与过去24小时平均疼痛强度(10分自评量表)相关(调整后的优势比[AOR] = 2.15,95%置信区间[CI] 1.21 - 3.80),以及过去24小时疼痛对一般活动的干扰(AOR 1.82 [95% CI 1.04 - 3.21])、行走能力(AOR 2.52 [95% CI 1.37 - 4.63])、身体能力(AOR 2.01 [95% CI 1.16 - 3.45])、睡眠(AOR 1.98 [95% CI 1.13 - 3.48])和生活乐趣(AOR 1.79 [95% CI 1.02 - 3.15])。

结论

疼痛和非医疗处方使用阿片类药物在注射毒品者中都很常见,且在本研究中高度相关。这些发现表明,需要做出更大努力,将预防性健康和服务导向这一人群。

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