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平山病手术结果的危险因素:一项大型队列的回顾性分析

Risk Factors for Surgical Results of Hirayama Disease: A Retrospective Analysis of a Large Cohort.

作者信息

Song Jian, Wang Hong-Li, Zheng Chao-Jun, Jiang Jian-Yuan

机构信息

Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.

Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.

出版信息

World Neurosurg. 2017 Sep;105:69-77. doi: 10.1016/j.wneu.2017.05.097. Epub 2017 May 27.

DOI:10.1016/j.wneu.2017.05.097
PMID:28559072
Abstract

OBJECTIVE

To explore risk factors affecting surgical results of Hirayama disease.

METHODS

A retrospective analysis of 210 patients was performed to identify risk factors affecting surgical results of Hirayama disease by using univariate and multivariate analyses. A receiver operating characteristic curve and area under the curve were applied to evaluate the significant results of the multivariate analysis and the optimal reference value.

RESULTS

The mean follow-up period was 27.3 months (range, 14-45 months), and 194 patients with clinical and radiographic data completed the final follow-up. Multivariate analysis identified age of patients (cutoff value 22.5 years), duration of the disease (cutoff value 33 months), physiologic reflex, and pathologic reflex as independent risk factors for surgical results of Hirayama disease. The receiver operating characteristic curve analysis and area under the curve showed that good reference value was obtained for the risk factors.

CONCLUSIONS

Age of patient, duration of the disease, physiologic reflex, and pathologic reflex are the main risk factors affecting surgical results of Hirayama disease. Receiver operating characteristic analysis shows that good reference value was obtained for the risk factors.

摘要

目的

探讨影响平山病手术效果的危险因素。

方法

对210例患者进行回顾性分析,采用单因素和多因素分析确定影响平山病手术效果的危险因素。应用受试者工作特征曲线及曲线下面积评估多因素分析的显著结果及最佳参考值。

结果

平均随访时间为27.3个月(范围14 - 45个月),194例有临床和影像学资料的患者完成了最终随访。多因素分析确定患者年龄(截断值22.5岁)、病程(截断值33个月)、生理反射和病理反射为影响平山病手术效果的独立危险因素。受试者工作特征曲线分析及曲线下面积显示这些危险因素具有良好的参考价值。

结论

患者年龄、病程、生理反射和病理反射是影响平山病手术效果的主要危险因素。受试者工作特征分析显示这些危险因素具有良好的参考价值。

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