Lim S K, Chung H C, Kim W T, Huh K B, Chung S S, Kim D I, Chung H J
Korean J Intern Med. 1986 Jul;1(2):266-71. doi: 10.3904/kjim.1986.1.2.266.
A case of an intracranial tumor in a 26-year old woman with symptoms of hypopituitarism, and visual disturbance is presented. The primary site has been verified by the clinical presentations and the hormonal and the neurological studies as originating from the pituitary gland with extension to the suprasellar area. Histologically, the tumor contains elements that demand its interpretation as a malignant teratoma. In a tumor marker study, the aFP level was elevated, suggestive of an endodermal sinus tumor component. We report this case as a mixed germ cell tumor originating from the pituitary gland with a suprasellar extension and a malignant transformation from a benign component.
本文报告一例26岁女性颅内肿瘤病例，该患者有垂体功能减退和视觉障碍症状。根据临床表现、激素及神经学检查，已证实肿瘤原发部位为垂体，并延伸至鞍上区域。组织学检查显示，肿瘤成分提示为恶性畸胎瘤。肿瘤标志物研究中，甲胎蛋白水平升高，提示存在内胚窦瘤成分。我们将该病例报告为起源于垂体并延伸至鞍上区域的混合性生殖细胞肿瘤，且由良性成分发生了恶性转化。
