Marshall L F, Rorke L B, Schut L
Childs Brain. 1979;5(2):96-102. doi: 10.1159/000119807.
Teratocarcinoma of the brain is a rare teratoid tumor. Less than 100 cases have been previously reported and only 4 were patients with tumors in the lateral ventricular system. At the Children's Hospital of Philadelphia, 2 patients with teratocarcinoma of the lateral ventricle of the brain have been treated in the past 5 years and both are long-term survivors. A third patient with a recurrence at University Hospital is now receiving chemotherapy. Our experience suggests that a combination of radical surgery, supervoltage radiotherapy and chemotherapy may be successful in controlling these neoplasms. Furthermore, since there is increasing evidence that they have a strong histologic relationship to the embryonal carcinomas that arise in the testes and elsewhere, it appears logical to apply chemotherapeutic strategies to these intracranial neoplasms based on experience with such tumors located in other regions of the body.
脑畸胎癌是一种罕见的类癌瘤。此前报道的病例不足100例，仅有4例患者的肿瘤位于侧脑室系统。在费城儿童医院，过去5年中有2例脑侧脑室畸胎癌患者接受了治疗，且均为长期存活者。在大学医院，第3例复发患者目前正在接受化疗。我们的经验表明，根治性手术、超高压放疗和化疗相结合可能成功控制这些肿瘤。此外，鉴于越来越多的证据表明它们与睾丸及其他部位发生的胚胎癌存在密切的组织学关系，基于对身体其他部位此类肿瘤的治疗经验，对这些颅内肿瘤应用化疗策略似乎是合理的。
