Gong Zhenhua, Han Meilin, Wu Yibo, Huang Xiong, Xu Wei-Jue, Lv Zhibzo
Department of Pediatric Surgery, Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai, China.
Eur J Pediatr Surg. 2018 Aug;28(4):373-377. doi: 10.1055/s-0037-1603092. Epub 2017 May 31.
Because of differences in therapy for first-time perianal abscess, a wide range of recurrences and/or development of fistula-in-ano (RF) rates have been reported. The indication for determining when surgical intervention is needed remains obscure and controversial. This retrospective study sought to compare outcomes of conservative treatment with those after incision and drainage (ID) to determine the optimal time for surgical intervention.
A total of 697 patients with first-time perianal abscess were included in this study. The median patient age at the time of onset was 129 days (range: 5-5,110 days). The median follow-up period was 395 days (range: 120-760 days).
Of the 697 patients with first-time perianal abscess, 355 (50.9%) patients who received conservative treatment had 12.7% (45/355) RF rate, which is less than that of abscesses treated with ID (24.6%, 72/297; < 0.001). The median course was 23 (2,466) days, which did not differ significantly from that of abscesses with ID (18 [3,510] days) ( = 0.609). Forty-six (6.6%) patients with abscesses that perforated spontaneously had 10.9% (5/46) RF rate, which was less than that of abscesses with ID ( = 0.019), and the median course was 9 (3,316) days, which was shorter than that of abscesses with ID ( = 0.04).
Conservative treatment is a safe and effective technique for most first-time perianal abscesses with less recurrence and a lower fistula formation rate. Incision must be performed when an abscess is likely to spread or shows no sign of spontaneous perforation.
由于首次肛周脓肿的治疗方法存在差异,已报道的肛瘘复发率和/或肛瘘形成率范围很广。确定何时需要手术干预的指征仍不明确且存在争议。这项回顾性研究旨在比较保守治疗与切开引流(ID)后的结果,以确定手术干预的最佳时机。
本研究共纳入697例首次肛周脓肿患者。发病时患者的中位年龄为129天(范围:5 - 5110天)。中位随访期为395天(范围:120 - 760天)。
在697例首次肛周脓肿患者中,355例(50.9%)接受保守治疗的患者肛瘘复发率为12.7%(45/355),低于接受切开引流治疗的脓肿患者(24.6%,72/297;P < 0.001)。中位病程为23(2466)天,与接受切开引流治疗的脓肿患者(18 [3510]天)无显著差异(P = 0.609)。46例(6.6%)脓肿自发穿孔的患者肛瘘复发率为10.9%(5/46),低于接受切开引流治疗的脓肿患者(P = 0.019),中位病程为9(3316)天,短于接受切开引流治疗的脓肿患者(P = 0.04)。
对于大多数首次肛周脓肿,保守治疗是一种安全有效的技术,复发率较低且肛瘘形成率较低。当脓肿可能扩散或无自发穿孔迹象时,必须进行切开。