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儿童肛周脓肿手术后治疗失败的危险因素。

Risk factors for therapy failure after surgery for perianal abscess in children.

作者信息

Doerner Johannes, Seiberth Rose, Jafarov Sakhavat, Zirngibl Hubert, Boenicke Lars

机构信息

Department of General and Visceral Surgery, Helios University Hospital Wuppertal, Witten/Herdecke University, Wuppertal, Germany.

出版信息

Front Surg. 2022 Dec 15;9:1065466. doi: 10.3389/fsurg.2022.1065466. eCollection 2022.

Abstract

PURPOSE

The role of surgery in managing perianal abscesses in the pediatric population is debatable, and data on recurrence risk is rare. This study aimed to evaluate the efficiency of surgery for a perianal abscess in children and identify parameters that predict recurrence.

METHODS

We performed a retrospective review of all children younger than age 14 requiring surgery for a perianal abscess from 2000 to 2018.

RESULTS

Out of 103 enrolled patients, 27 (26%) had recurrent perianal disease. Recurrences appeared after a median of 5 months (range: 1-18 months), in 12 cases as perianal abscess and 15 cases as fistula . Anal fistula probing was performed in 33% of all patients, of which 16 (15%) underwent fistulotomy. In univariate analysis, older age ( = 0.034), fistula probing ( = 0.006) and fistulotomy ( = 0.009) was associated with treatment success. History of perianal abscess, multilocal occurrence, and the presence of enteric flora in wound swabs was associated with treatment failure ( = 0.002, OR = 0.032). In multivariate analysis, anal fistula probing was independently associated with treatment success ( = 0.019, OR = 22.08), while the history of perianal abscess was associated with treatment failure ( = 0.002, OR = 0.032).

CONCLUSION

Our study identified probing for fistula as a predictor of therapy success, while the history of perianal abscess was identified as a predictor of treatment failure. Therefore, in all children with perianal abscess, fistula probing and if present, fistulotomy should be performed.

摘要

目的

手术在小儿肛周脓肿治疗中的作用存在争议,且关于复发风险的数据较少。本研究旨在评估小儿肛周脓肿手术的疗效,并确定预测复发的参数。

方法

我们对2000年至2018年期间所有14岁以下因肛周脓肿需要手术治疗的儿童进行了回顾性研究。

结果

在103例入组患者中,27例(26%)出现肛周疾病复发。复发中位时间为5个月(范围:1 - 18个月),其中12例为肛周脓肿复发,15例为肛瘘复发。33%的患者进行了肛瘘探查,其中16例(15%)接受了肛瘘切开术。单因素分析显示,年龄较大(P = 0.034)、肛瘘探查(P = 0.006)和肛瘘切开术(P = 0.009)与治疗成功相关。肛周脓肿病史、多部位发病以及伤口拭子中存在肠道菌群与治疗失败相关(P = 0.002,OR = 0.032)。多因素分析显示,肛瘘探查与治疗成功独立相关(P = 0.019,OR = 22.08),而肛周脓肿病史与治疗失败相关(P = 0.002,OR = 0.032)。

结论

我们的研究确定肛瘘探查是治疗成功的预测因素,而肛周脓肿病史是治疗失败的预测因素。因此,对于所有肛周脓肿患儿,均应进行肛瘘探查,如有肛瘘则应行肛瘘切开术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e78d/9797814/57ecce223555/fsurg-09-1065466-g001.jpg

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