镉与人类精子染色质的锌依赖性稳定性相互作用。
Cadmium interacts with the zinc-dependent stability of the human sperm chromatin.
作者信息
Casswall T H, Björndahl L, Kvist U
机构信息
Department of Physiology, Karolinska Institutet, Stockholm, Sweden.
出版信息
J Trace Elem Electrolytes Health Dis. 1987 Dec;1(2):85-7.
PMID:2856574
Abstract
Zinc normally participates in the stabilization of the chromatin of human spermatozoa, which have a high content of zinc after ejaculation. Sperm chromatin, depleted of zinc with EDTA, regained stability in the detergent SDS after exposure to Cd2+ in vitro. This effect was reversible with EDTA, but albumin could not reverse the stabilization caused by Cd2+ to the same extent as it reversed the stabilization caused by Zn2+.
摘要
锌通常参与人类精子染色质的稳定，射精后精子含有高含量的锌。用乙二胺四乙酸（EDTA）去除锌的精子染色质，在体外暴露于镉离子（Cd2+）后，在去污剂十二烷基硫酸钠（SDS）中恢复了稳定性。这种作用可用EDTA逆转，但白蛋白不能像逆转锌离子（Zn2+）引起的稳定性那样，同等程度地逆转镉离子引起的稳定性。
Zotero 插件