Nie Yijun, Zhang Zhanglin, Wu Hong, Wan Lagen
Department of Clinical Laboratory, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Institute of Blood Transfusion, Jiangxi Province Blood Center, Nanchang, Jiangxi 330052, P.R. China.
Exp Ther Med. 2017 May;13(5):2480-2482. doi: 10.3892/etm.2017.4241. Epub 2017 Mar 20.
Hemophagocytic lymphohistiocytosis (HLH), also termed hemophagocytic syndrome, is a severe, life-threatening inflammatory condition that results from an excessive, prolonged and ineffective immune response. The syndrome occurs due to overactive macrophages from the bone marrow or lymph tissue that phagocytose erythrocytes leukocytes and platelets. HLH in a patient with human immunodeficiency virus infection has rarely been studied. The present case study described an uncommon case of this syndrome in combination with human immunodeficiency virus infection in a patient, who eventually succumbed to severe infection and multiple organ failure following the refusal of medical treatment.
噬血细胞性淋巴组织细胞增生症（HLH），也称为噬血细胞综合征，是一种严重的、危及生命的炎症性疾病，由过度、持久且无效的免疫反应引起。该综合征是由于骨髓或淋巴组织中的巨噬细胞过度活跃，吞噬红细胞、白细胞和血小板所致。人类免疫缺陷病毒感染患者的HLH鲜有研究。本病例研究描述了一名患者同时患有这种综合征和人类免疫缺陷病毒感染的罕见病例，该患者在拒绝接受治疗后最终死于严重感染和多器官衰竭。
