Zimmermann Nicolle, Mograbi Daniel C, Hermes-Pereira Andressa, Fonseca Rochele P, Prigatano George P
a Department of Radiology , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.
d Department of Psychology-Human Cognition , PUCRS , Porto Alegre , Brazil.
Cogn Neuropsychiatry. 2017 Jul;22(4):346-360. doi: 10.1080/13546805.2017.1330191. Epub 2017 May 31.
The purpose of this study was to investigate the contribution of executive functions (EF) components and episodic and working memory variables, as well as clinical and demographic factors, to awareness of cognitive ability in traumatic brain injury (TBI).
Sixty-five TBI patients (mild: n = 26; moderate/severe: n = 39) took part in the study. Independent stepwise regression models were calculated for EF and memory predictors, with awareness being measured by patient/informant discrepancy in the Patient Competency Rating Scale.
Models with EF variables indicated that semantic verbal fluency and age are the best predictors of awareness, whereas models including mnemonic functions suggested verbal delayed episodic recall and TBI severity as predictors.
These results are discussed in relation to clinical implications, such as the need to focus efforts of rehabilitation in the cognitive abilities related to awareness, and theoretical models.
本研究旨在探讨执行功能（EF）成分、情景记忆和工作记忆变量以及临床和人口统计学因素对创伤性脑损伤（TBI）患者认知能力意识的影响。
65名TBI患者（轻度：n = 26；中度/重度：n = 39）参与了本研究。计算了EF和记忆预测因子的独立逐步回归模型，通过患者能力评定量表中患者/ informant差异来衡量意识。
含EF变量的模型表明，语义言语流畅性和年龄是意识的最佳预测因子，而包含记忆功能的模型则提示言语延迟情景回忆和TBI严重程度为预测因子。
结合临床意义（如需要将康复工作重点放在与意识相关的认知能力上）和理论模型对这些结果进行了讨论。
