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子宫内膜癌前哨淋巴结图谱绘制与分期:妇科肿瘤学会文献综述及共识推荐

Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations.

作者信息

Holloway Robert W, Abu-Rustum Nadeem R, Backes Floor J, Boggess John F, Gotlieb Walter H, Jeffrey Lowery W, Rossi Emma C, Tanner Edward J, Wolsky Rebecca J

机构信息

Florida Hospital Cancer Institute, Orlando, FL, USA.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

出版信息

Gynecol Oncol. 2017 Aug;146(2):405-415. doi: 10.1016/j.ygyno.2017.05.027. Epub 2017 May 28.

DOI:10.1016/j.ygyno.2017.05.027
PMID:28566221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6075736/
Abstract

The emphasis in contemporary medical oncology has been "precision" or "personalized" medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar attempts at precision are occurring in surgical oncology. Sentinel lymph node (SLN) mapping has recently been introduced into the surgical staging of endometrial cancer with the goal to reduce morbidity associated with comprehensive lymphadenectomy, yet obtain prognostic information from lymph node status. The Society of Gynecologic Oncology's (SGO) Clinical Practice Committee and SLN Working Group reviewed the current literature for preparation of this document. Literature-based recommendations for the inclusion of SLN assessment in the treatment of patients with endometrial cancer are presented. This article examines.

摘要

当代医学肿瘤学的重点是“精准”或“个性化”医疗,这些术语意味着一种通过靶向治疗提高疗效的策略。外科肿瘤学也在进行类似的精准尝试。前哨淋巴结(SLN) mapping最近已被引入子宫内膜癌的手术分期,目的是降低与全面淋巴结清扫相关的发病率,同时从淋巴结状态中获取预后信息。妇科肿瘤学会(SGO)的临床实践委员会和SLN工作组回顾了当前文献以编写本文件。本文提出了基于文献的关于将SLN评估纳入子宫内膜癌患者治疗的建议。本文进行了探讨。

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Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations.子宫内膜癌前哨淋巴结图谱绘制与分期:妇科肿瘤学会文献综述及共识推荐
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Best Pract Res Clin Obstet Gynaecol. 2015 Aug;29(6):845-57. doi: 10.1016/j.bpobgyn.2015.02.007. Epub 2015 Mar 4.

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Gynecol Oncol Rep. 2025 Aug 4;60:101919. doi: 10.1016/j.gore.2025.101919. eCollection 2025 Aug.
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Implementation of a Personalized Risk Model for Lymph Node Metastasis in Endometrial Carcinoma: Healthcare Providers' Perspectives on Use, Barriers, and Facilitators.子宫内膜癌淋巴结转移个性化风险模型的实施:医疗服务提供者对其使用、障碍和促进因素的看法
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本文引用的文献

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A Prospective Cohort Study Comparing Colorimetric and Fluorescent Imaging for Sentinel Lymph Node Mapping in Endometrial Cancer.一项比较比色成像与荧光成像用于子宫内膜癌前哨淋巴结定位的前瞻性队列研究。
Ann Surg Oncol. 2017 Jul;24(7):1972-1979. doi: 10.1245/s10434-017-5825-3. Epub 2017 Mar 6.
2
Survival of Patients with Serous Uterine Carcinoma Undergoing Sentinel Lymph Node Mapping.接受前哨淋巴结定位的浆液性子宫癌患者的生存情况
Ann Surg Oncol. 2017 Jul;24(7):1965-1971. doi: 10.1245/s10434-017-5816-4. Epub 2017 Mar 3.
3
A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study.
Cancer of the corpus uteri: A 2025 update.
子宫体癌:2025年最新进展
Int J Gynaecol Obstet. 2025 Sep;171 Suppl 1:60-77. doi: 10.1002/ijgo.70326. Epub 2025 Jul 7.
4
Sentinel Node Biopsy Using Two Concurrent Labeling Techniques (Radioactive Tracer With/Without Blue Dye vs. Indocyanin Green-ICG) in Early-Stage Endometrial Cancer Patients (TESLA-1): A Prospective Observational Study CEEGOG EX-02.在早期子宫内膜癌患者中使用两种同步标记技术(放射性示踪剂加/不加蓝色染料与吲哚菁绿-ICG)进行前哨淋巴结活检(TESLA-1):一项前瞻性观察性研究CEEGOG EX-02。
Cancers (Basel). 2025 May 9;17(10):1606. doi: 10.3390/cancers17101606.
5
The impact of lymphadenectomy on cancerspecific survival in patients with low-grade endometrioid carcinoma of stage T1a.淋巴结切除术对T1a期低级别子宫内膜样癌患者癌症特异性生存的影响。
Sci Rep. 2025 May 7;15(1):15952. doi: 10.1038/s41598-025-00531-3.
6
Comparison of tracer application methods for sentinel lymph node detection in open surgery patients with endometrial cancer: a retrospective cohort study.子宫内膜癌开放手术患者前哨淋巴结检测中示踪剂应用方法的比较:一项回顾性队列研究
BMC Cancer. 2025 Apr 8;25(1):638. doi: 10.1186/s12885-025-14037-8.
7
Cervical injection as an alternative to the utero-ovarian ligament for mapping pelvic sentinel lymph node in early-stage ovarian cancer.宫颈注射作为子宫卵巢韧带的替代方法用于早期卵巢癌盆腔前哨淋巴结的定位。
Arch Gynecol Obstet. 2025 May;311(5):1407-1414. doi: 10.1007/s00404-025-07984-x. Epub 2025 Apr 5.
8
Enhancing Sentinel Lymph Node Biopsy in Endometrial Cancer Using Augmented and Mixed Reality.使用增强现实和混合现实技术提高子宫内膜癌前哨淋巴结活检水平
Cureus. 2025 Jan 17;17(1):e77599. doi: 10.7759/cureus.77599. eCollection 2025 Jan.
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The Assessment of Sentinel Lymph Node Mapping Methods in Endometrial Cancer.子宫内膜癌前哨淋巴结定位方法的评估
J Clin Med. 2025 Jan 21;14(3):676. doi: 10.3390/jcm14030676.
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Radiotherapy improves stress urinary incontinence but impairs pelvic floor function in endometrial cancer patients: a prospective cohort study.放射治疗可改善子宫内膜癌患者的压力性尿失禁,但会损害其盆底功能:一项前瞻性队列研究。
Arch Gynecol Obstet. 2025 Apr;311(4):1133-1139. doi: 10.1007/s00404-025-07964-1. Epub 2025 Jan 30.
比较前哨淋巴结活检与淋巴结切除术用于子宫内膜癌分期的研究(FIRES 试验):一项多中心、前瞻性、队列研究。
Lancet Oncol. 2017 Mar;18(3):384-392. doi: 10.1016/S1470-2045(17)30068-2. Epub 2017 Feb 1.
4
Disparities in the surgical staging of high-grade endometrial cancer in the United States.美国高级别子宫内膜癌手术分期的差异。
Gynecol Oncol Res Pract. 2017 Jan 19;4:1. doi: 10.1186/s40661-016-0036-3. eCollection 2017.
5
Impact of sentinel lymph node mapping on recurrence patterns in endometrial cancer.前哨淋巴结 mapping 对子宫内膜癌复发模式的影响。 (注:这里“mapping”常见释义为“绘制地图”等,在医学语境中可能有更专业的含义,比如“定位”等,具体需结合专业知识准确理解,但仅按要求翻译为“mapping” )
Gynecol Oncol. 2017 Mar;144(3):503-509. doi: 10.1016/j.ygyno.2017.01.013. Epub 2017 Jan 16.
6
Patients with endometrial cancer at risk for lymphatic metastasis should undergo pelvic and periaortic lymphadenectomy as part of their initial surgery.
Cancer. 2017 Jan 1;123(2):192-196. doi: 10.1002/cncr.30418. Epub 2016 Nov 7.
7
Indocyanine green fluorescence imaging of lymph nodes during robotic-assisted laparoscopic operation for endometrial cancer. A prospective validation study using a sentinel lymph node surgical algorithm.机器人辅助腹腔镜子宫内膜癌手术中淋巴结的吲哚菁绿荧光成像。一项使用前哨淋巴结手术算法的前瞻性验证研究。
Gynecol Oncol. 2016 Dec;143(3):479-483. doi: 10.1016/j.ygyno.2016.10.029. Epub 2016 Oct 21.
8
Performance of sentinel lymph node biopsy in high-risk endometrial cancer.前哨淋巴结活检在高危子宫内膜癌中的应用
Gynecol Oncol Rep. 2016 Apr 19;17:69-71. doi: 10.1016/j.gore.2016.04.002. eCollection 2016 Aug.
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Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial.前哨淋巴结活检阳性黑色素瘤患者完全淋巴结清扫与不清扫(DeCOG-SLT):一项多中心、随机、III 期临床试验。
Lancet Oncol. 2016 Jun;17(6):757-767. doi: 10.1016/S1470-2045(16)00141-8. Epub 2016 May 5.
10
Sentinel lymph node mapping with staging lymphadenectomy for patients with endometrial cancer increases the detection of metastasis.对子宫内膜癌患者进行前哨淋巴结定位并分期行淋巴结切除术可提高转移灶的检出率。
Gynecol Oncol. 2016 May;141(2):206-210. doi: 10.1016/j.ygyno.2016.02.018. Epub 2016 Mar 2.