Holloway Robert W, Abu-Rustum Nadeem R, Backes Floor J, Boggess John F, Gotlieb Walter H, Jeffrey Lowery W, Rossi Emma C, Tanner Edward J, Wolsky Rebecca J
Florida Hospital Cancer Institute, Orlando, FL, USA.
Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gynecol Oncol. 2017 Aug;146(2):405-415. doi: 10.1016/j.ygyno.2017.05.027. Epub 2017 May 28.
The emphasis in contemporary medical oncology has been "precision" or "personalized" medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar attempts at precision are occurring in surgical oncology. Sentinel lymph node (SLN) mapping has recently been introduced into the surgical staging of endometrial cancer with the goal to reduce morbidity associated with comprehensive lymphadenectomy, yet obtain prognostic information from lymph node status. The Society of Gynecologic Oncology's (SGO) Clinical Practice Committee and SLN Working Group reviewed the current literature for preparation of this document. Literature-based recommendations for the inclusion of SLN assessment in the treatment of patients with endometrial cancer are presented. This article examines.
当代医学肿瘤学的重点是“精准”或“个性化”医疗,这些术语意味着一种通过靶向治疗提高疗效的策略。外科肿瘤学也在进行类似的精准尝试。前哨淋巴结(SLN) mapping最近已被引入子宫内膜癌的手术分期,目的是降低与全面淋巴结清扫相关的发病率,同时从淋巴结状态中获取预后信息。妇科肿瘤学会(SGO)的临床实践委员会和SLN工作组回顾了当前文献以编写本文件。本文提出了基于文献的关于将SLN评估纳入子宫内膜癌患者治疗的建议。本文进行了探讨。