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三维打印心脏模型辅助复杂先天性心脏病特定病例的手术决策和术前规划:资源有限环境下的早期经验与概念验证

Three-dimensional-printed cardiac prototypes aid surgical decision-making and preoperative planning in selected cases of complex congenital heart diseases: Early experience and proof of concept in a resource-limited environment.

作者信息

Kappanayil Mahesh, Koneti Nageshwara Rao, Kannan Rajesh R, Kottayil Brijesh P, Kumar Krishna

机构信息

Department of Pediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.

Department of Pediatric Cardiology, CARE Hospitals, Hyderabad, Telangana, India.

出版信息

Ann Pediatr Cardiol. 2017 May-Aug;10(2):117-125. doi: 10.4103/apc.APC_149_16.

Abstract

INTRODUCTION

Three-dimensional. (3D) printing is an innovative manufacturing process that allows computer-assisted conversion of 3D imaging data into physical "printouts" Healthcare applications are currently in evolution.

OBJECTIVE

The objective of this study was to explore the feasibility and impact of using patient-specific 3D-printed cardiac prototypes derived from high-resolution medical imaging data (cardiac magnetic resonance imaging/computed tomography [MRI/CT]) on surgical decision-making and preoperative planning in selected cases of complex congenital heart diseases (CHDs).

MATERIALS AND METHODS

Five patients with complex CHD with previously unresolved management decisions were chosen. These included two patients with complex double-outlet right ventricle, two patients with criss-cross atrioventricular connections, and one patient with congenitally corrected transposition of great arteries with pulmonary atresia. Cardiac MRI was done for all patients, cardiac CT for one; specific surgical challenges were identified. Volumetric data were used to generate patient-specific 3D models. All cases were reviewed along with their 3D models, and the impact on surgical decision-making and preoperative planning was assessed.

RESULTS

Accurate life-sized 3D cardiac prototypes were successfully created for all patients. The models enabled radically improved 3D understanding of anatomy, identification of specific technical challenges, and precise surgical planning. Augmentation of existing clinical and imaging data by 3D prototypes allowed successful execution of complex surgeries for all five patients, in accordance with the preoperative planning.

CONCLUSIONS

3D-printed cardiac prototypes can radically assist decision-making, planning, and safe execution of complex congenital heart surgery by improving understanding of 3D anatomy and allowing anticipation of technical challenges.

摘要

引言

三维(3D)打印是一种创新的制造工艺,可将3D成像数据通过计算机辅助转换为实体“打印件”。目前,其在医疗保健领域的应用正在不断发展。

目的

本研究的目的是探讨在特定复杂先天性心脏病(CHD)病例中,使用源自高分辨率医学成像数据(心脏磁共振成像/计算机断层扫描[MRI/CT])的患者特异性3D打印心脏模型对手术决策和术前规划的可行性及影响。

材料与方法

选取5例之前管理决策未解决的复杂CHD患者。其中包括2例复杂右心室双出口患者、2例十字交叉房室连接患者和1例先天性矫正型大动脉转位合并肺动脉闭锁患者。所有患者均进行了心脏MRI检查,1例进行了心脏CT检查;确定了具体的手术挑战。利用容积数据生成患者特异性3D模型。对所有病例及其3D模型进行了回顾,并评估了其对手术决策和术前规划的影响。

结果

成功为所有患者创建了精确的实物大小3D心脏模型。这些模型使对解剖结构的3D理解得到了极大改善,明确了具体技术挑战,并进行了精确的手术规划。3D模型对现有临床和影像数据的补充,使所有5例患者均能按照术前规划成功实施复杂手术。

结论

3D打印心脏模型可通过增进对3D解剖结构的理解并提前预估技术挑战,从根本上辅助复杂先天性心脏病手术的决策、规划及安全实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6f/5431022/e85b4cf024e4/APC-10-117-g002.jpg

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