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一期缝合颈动脉内膜切除术的结果

Outcomes of Carotid Endarterectomy with Primary Closure.

作者信息

Cheng Ivy, Vyas Krishna S, Velaga Santhosh, Davenport Daniel L, Saha Sibu P

机构信息

Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Mayo Clinic, Rochester, Minnesota.

出版信息

Int J Angiol. 2017 Jun;26(2):83-88. doi: 10.1055/s-0037-1601053. Epub 2017 Mar 14.

Abstract

Carotid endarterectomy (CEA) reduces the risk of stroke in patients with internal carotid artery stenosis, although the optimal surgical technique is debated. The literature suggests that patch angioplasty reduces complication risk, although primary closure shortens cross-clamp time and eliminates complications associated with grafts. The objective of this study was to assess the complication rate after CEA with primary closure. Retrospective review of 240 consecutive patients between 2002 and 2010. Of these patients, 70% returned for follow-up visits for at least 2 or more years. Primary closure was used in all patients. The average cross-clamp time was 18 minutes. Complications in the immediate postoperative period within 30 days were as follows: stroke ( = 3; 1.1%), transient ischemic attack (TIA;  = 4; 1.5%), myocardial infarction (MI;  = 3; 1.1%), and death ( = 1; 0.4%). Short-term follow-up revealed eight patients who were found to have significant restenosis (>80%) by carotid duplex imaging. Two to ten year postoperative complication rates were as follows: stroke ( = 7; 4.2%), TIA ( = 7; 4.2%), amaurosis fugax ( = 1; 0.6%), MI ( = 8; 4.8%), and death ( = 28; 17%). Mortality was due to stroke or heart attack ( = 2; 1.2%), cancer ( = 7; 4.2%), and unknown causes ( = 19; 11%). This study presents our experience with complications after primary closure after CEA. In our experience, CEA is a safe and effective surgical means of preventing stroke in the short term. Well-designed prospective studies are needed to confirm specific patient characteristics in which primary closure and patch angioplasty are indicated.

摘要

颈动脉内膜切除术(CEA)可降低颈内动脉狭窄患者的中风风险,尽管最佳手术技术仍存在争议。文献表明,补片血管成形术可降低并发症风险,而一期缝合可缩短夹闭时间并消除与移植物相关的并发症。本研究的目的是评估一期缝合CEA后的并发症发生率。对2002年至2010年间连续的240例患者进行回顾性研究。其中,70%的患者返回进行了至少2年或更长时间的随访。所有患者均采用一期缝合。平均夹闭时间为18分钟。术后30天内的近期并发症如下:中风(n = 3;1.1%)、短暂性脑缺血发作(TIA;n = 4;1.5%)、心肌梗死(MI;n = 3;1.1%)和死亡(n = 1;0.4%)。短期随访发现8例患者经颈动脉双功超声成像显示有严重再狭窄(>80%)。术后2至10年的并发症发生率如下:中风(n = 7;4.2%)、TIA(n = 7;4.2%)、一过性黑矇(n = 1;0.6%)、MI(n = 8;4.8%)和死亡(n = 28;17%)。死亡原因是中风或心脏病发作(n = 2;1.2%)、癌症(n = 7;4.2%)和不明原因(n = 19;11%)。本研究展示了我们在CEA一期缝合后并发症方面的经验。根据我们的经验,CEA是短期内预防中风的一种安全有效的手术方法。需要设计良好的前瞻性研究来确定适合一期缝合和补片血管成形术的特定患者特征。

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Outcomes of Carotid Endarterectomy with Primary Closure.一期缝合颈动脉内膜切除术的结果
Int J Angiol. 2017 Jun;26(2):83-88. doi: 10.1055/s-0037-1601053. Epub 2017 Mar 14.

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